Methocarbamol and Fracture nonunion - a phase IV clinical study of FDA data

Summary:

Fracture nonunion is reported as a side effect among people who take Methocarbamol (methocarbamol), especially for people who are female, 60+ old, also take Actonel, and have Osteoporosis.

The phase IV clinical study analyzes which people have Fracture nonunion when taking Methocarbamol. It is created by eHealthMe based on reports of 16,788 people who have side effects when taking Methocarbamol from the FDA, and is updated regularly.

What is Methocarbamol?

Methocarbamol has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 17,766 Methocarbamol users. Check the latest studies of Methocarbamol.

What is Fracture nonunion?

Fracture nonunion (permanent failure of healing following a broken bone) is found to be associated with 311 drugs and 370 conditions by eHealthMe. Check the latest studies of Fracture nonunion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

16,788 people reported to have side effects when taking Methocarbamol.
Among them, 17 people (0.1%) have Fracture nonunion.

Could Methocarbamol cause Fracture nonunion?

Among these 17 people:

What is the gender of people who have Fracture nonunion when taking Methocarbamol? *

female: 87.5 %
male: 12.5 %

What is the age of people who have Fracture nonunion when taking Methocarbamol? *

What are other drugs people take besides Methocarbamol? *

What are other side effects people have besides Fracture nonunion? *

Femur Fracture: 15 people, 88.24%
Joint Pain: 15 people, 88.24%
Pain In Extremity: 13 people, 76.47%
Fall: 11 people, 64.71%
Groin Pain: 10 people, 58.82%
Limb Asymmetry (consistent task discrepancy between the two lower limbs): 7 people, 41.18%
Anaemia Postoperative: 7 people, 41.18%
Gait Disturbance: 7 people, 41.18%
Device Failure: 7 people, 41.18%
Impaired Healing: 6 people, 35.29%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 10 people, 58.82%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 17.65%
Thyroid Diseases: 2 people, 11.76%
Quit Smoking: 2 people, 11.76%
High Blood Cholesterol: 1 person, 5.88%
Birth Control: 1 person, 5.88%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 5.88%
Depression: 1 person, 5.88%
Diabetes: 1 person, 5.88%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Methocarbamol and have Fracture nonunion?

- Check whether Fracture nonunion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methocarbamol:

Methocarbamol (17,766 reports)

Browse all side effects of Methocarbamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fracture nonunion:

Fracture nonunion (311 drugs)

Browse all the conditions that are associated with Fracture nonunion:

Fracture nonunion (370 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methocarbamol (the active ingredients of Methocarbamol) and Methocarbamol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.