Methotrexate sodium and Spinal cord disorder - a phase IV clinical study of FDA data

Summary:

Spinal cord disorder is reported as a side effect among people who take Methotrexate sodium (methotrexate sodium), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Cyclophosphamide, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Spinal cord disorder when taking Methotrexate sodium. It is created by eHealthMe based on reports of 96,366 people who have side effects when taking Methotrexate sodium from the FDA, and is updated regularly.

What is Methotrexate sodium?

Methotrexate sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 97,679 Methotrexate sodium users. Check the latest studies of Methotrexate sodium.

What is Spinal cord disorder?

Spinal cord disorder (disease of spinal cord) is found to be associated with 319 drugs and 377 conditions by eHealthMe. Check the latest studies of Spinal cord disorder.

On Jul, 06, 2026

96,366 people reported to have side effects when taking Methotrexate sodium.
Among them, 18 people (0.02%) have Spinal cord disorder.

Could Methotrexate sodium cause Spinal cord disorder?

Among these 18 people:

How long have people been on Methotrexate sodium when they have Spinal cord disorder? *

What is the gender of people who have Spinal cord disorder when taking Methotrexate sodium? *

female: 64.71 %
male: 35.29 %

What is the age of people who have Spinal cord disorder when taking Methotrexate sodium? *

What are other drugs people take besides Methotrexate sodium? *

What are other side effects people have besides Spinal cord disorder? *

Weakness: 5 people, 27.78%
Diarrhea: 4 people, 22.22%
Faecal Incontinence (a lack of control over passing stool): 3 people, 16.67%
Weight Decreased: 3 people, 16.67%
Insomnia (sleeplessness): 3 people, 16.67%
Gallbladder Enlargement: 2 people, 11.11%
Escherichia Infection (bacterial infection by escherichia coli): 2 people, 11.11%
Exposed Bone In Jaw: 2 people, 11.11%
Intervertebral Disc Degeneration (spinal disc degeneration): 2 people, 11.11%
Fall: 2 people, 11.11%

What are the existing conditions these people have? *

Vitamin B Complex Deficiency: 2 people, 11.11%
Pain: 2 people, 11.11%
Osteoporosis (bones weak and more likely to break): 2 people, 11.11%
Blood Thyroid Stimulating Hormone Decreased: 2 people, 11.11%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 11.11%
Lymphoma (cancer that begins in immune system cells): 1 person, 5.56%
Leukocytosis (increased white blood cells): 1 person, 5.56%
Leukaemic Infiltration Brain (blood cancer cells affects the brain): 1 person, 5.56%
Leukaemia (blood or bone marrow cancer): 1 person, 5.56%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Methotrexate sodium and have Spinal cord disorder?

- Check whether Spinal cord disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methotrexate sodium:

Methotrexate sodium (97,679 reports)

Browse all side effects of Methotrexate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spinal cord disorder:

Spinal cord disorder (319 drugs)

Browse all the conditions that are associated with Spinal cord disorder:

Spinal cord disorder (377 conditions)

Related publications that referenced our studies

Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on methotrexate sodium (the active ingredients of Methotrexate sodium) and Methotrexate sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.