Methyldopa and Septic shock - a phase IV clinical study of FDA data

Summary:

Septic shock is reported as a side effect among people who take Methyldopa (methyldopa), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Pindolol, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Septic shock when taking Methyldopa. It is created by eHealthMe based on reports of 6,345 people who have side effects when taking Methyldopa from the FDA, and is updated regularly.

What is Methyldopa?

Methyldopa has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 6,475 Methyldopa users. Check the latest studies of Methyldopa.

What is Septic shock?

Septic shock (shock due to blood infection) is found to be associated with 1,731 drugs and 3,400 conditions by eHealthMe. Check the latest studies of Septic shock.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

6,345 people reported to have side effects when taking Methyldopa.
Among them, 11 people (0.17%) have Septic shock.

Among these 11 people:

How long have people been on Methyldopa when they have Septic shock? *

What is the gender of people who have Septic shock when taking Methyldopa? *

female: 54.55 %
male: 45.45 %

What is the age of people who have Septic shock when taking Methyldopa? *

What are other drugs people take besides Methyldopa? *

What are other side effects people have besides Septic shock? *

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 36.36%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 3 people, 27.27%
Pneumonia: 3 people, 27.27%
Renal Impairment (severely reduced kidney function): 2 people, 18.18%
Fever: 2 people, 18.18%
Subarachnoid Haemorrhage (blood leaks into the space between two membranes that surround the brain): 2 people, 18.18%
Multi-Organ Failure (multisystem organ failure): 2 people, 18.18%
Pleural Effusion (water on the lungs): 2 people, 18.18%
Dehydration (dryness resulting from the removal of water): 1 person, 9.09%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 1 person, 9.09%

What are the existing conditions these people have? *

Dermatophytosis (inflammation of the skin and underlying muscle tissue): 2 people, 18.18%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 18.18%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 9.09%
Pneumonia: 1 person, 9.09%
Iga Nephropathy (kidney disease- condition prevents the kidneys from filtering waste): 1 person, 9.09%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 9.09%
High Blood Cholesterol: 1 person, 9.09%
Fungal Infection: 1 person, 9.09%
Diabetes: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Methyldopa and have Septic shock?

- Check whether Septic shock is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methyldopa:

Methyldopa (6,475 reports)

Septic shock treatments and more:

Septic shock (51,128 reports)

Browse all side effects of Methyldopa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Septic shock:

Septic shock (1,731 drugs)

Browse all the conditions that are associated with Septic shock:

Septic shock (3,400 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methyldopa (the active ingredients of Methyldopa) and Methyldopa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.