Methylphenidate and Acute upper airway obstruction - a phase IV clinical study of FDA data

Summary:

Acute upper airway obstruction is reported as a side effect among people who take Methylphenidate (methylphenidate), especially for people who are female, 40-49 old, also take Zopiclone, and have Acne.

The phase IV clinical study analyzes which people have Acute upper airway obstruction when taking Methylphenidate. It is created by eHealthMe based on reports of 8,120 people who have side effects when taking Methylphenidate from the FDA, and is updated regularly.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,217 Methylphenidate users. Check the latest studies of Methylphenidate.

What is Acute upper airway obstruction?

Acute upper airway obstruction (blockage occurs in the upper airway) is found to be associated with 1,043 drugs and 1,895 conditions by eHealthMe. Check the latest studies of Acute upper airway obstruction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

8,120 people reported to have side effects when taking Methylphenidate.
Among them, 14 people (0.17%) have Acute upper airway obstruction.

Could Methylphenidate cause Acute upper airway obstruction?

Among these 14 people:

What is the gender of people who have Acute upper airway obstruction when taking Methylphenidate? *

female: 92.86 %
male: 7.14 %

What is the age of people who have Acute upper airway obstruction when taking Methylphenidate? *

What are other drugs people take besides Methylphenidate? *

What are other side effects people have besides Acute upper airway obstruction? *

Nausea (feeling of having an urge to vomit): 8 people, 57.14%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 50.00%
Dyspnea (difficult or laboured breathing): 7 people, 50.00%
Cough: 7 people, 50.00%
Headache (pain in head): 7 people, 50.00%
Back Pain: 7 people, 50.00%
Neck Pain: 7 people, 50.00%
Itching: 7 people, 50.00%
Nausea And Vomiting: 5 people, 35.71%
Infusion Related Reaction: 4 people, 28.57%

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 28.57%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 28.57%
Insomnia (sleeplessness): 4 people, 28.57%
Cervical Spinal Stenosis (narrowing of the spinal canal in the neck): 4 people, 28.57%
Acne (skin problems that cause pimples): 4 people, 28.57%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 21.43%
Joint Pain: 3 people, 21.43%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 21.43%
Drug Hypersensitivity: 2 people, 14.29%
Drowsiness: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Methylphenidate and have Acute upper airway obstruction?

- Check whether Acute upper airway obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methylphenidate:

Methylphenidate (8,217 reports)

Browse all side effects of Methylphenidate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute upper airway obstruction:

Acute upper airway obstruction (1,043 drugs)

Browse all the conditions that are associated with Acute upper airway obstruction:

Acute upper airway obstruction (1,895 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate (the active ingredients of Methylphenidate) and Methylphenidate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.