Methylphenidate and Coma - a phase IV clinical study of FDA data

Summary:

Coma is reported as a side effect among people who take Methylphenidate (methylphenidate), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Diazepam, and have Personality disorder.

The phase IV clinical study analyzes which people have Coma when taking Methylphenidate. It is created by eHealthMe based on reports of 8,120 people who have side effects when taking Methylphenidate from the FDA, and is updated regularly.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,216 Methylphenidate users. Check the latest studies of Methylphenidate.

What is Coma?

Coma (state of unconsciousness lasting more than six hours) is found to be associated with 2,785 drugs and 3,207 conditions by eHealthMe. Check the latest studies of Coma.

On Jun, 10, 2026

8,120 people reported to have side effects when taking Methylphenidate.
Among them, 53 people (0.65%) have Coma.

Among these 53 people:

How long have people been on Methylphenidate when they have Coma? *

What is the gender of people who have Coma when taking Methylphenidate? *

female: 22.45 %
male: 77.55 %

What is the age of people who have Coma when taking Methylphenidate? *

What are other drugs people take besides Methylphenidate? *

What are other side effects people have besides Coma? *

Urinary Retention (the inability to completely or partially empty the bladder): 23 people, 43.40%
Suicide Attempt: 21 people, 39.62%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 20 people, 37.74%
Depression: 20 people, 37.74%
Confusional State: 17 people, 32.08%
Drug Abuse: 16 people, 30.19%
Agitation (state of anxiety or nervous excitement): 13 people, 24.53%
Drug Ineffective: 11 people, 20.75%
Poisoning: 11 people, 20.75%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 10 people, 18.87%

What are the existing conditions these people have? *

Personality Disorder: 4 people, 7.55%
Stress And Anxiety: 3 people, 5.66%
Psychotic Disorder: 3 people, 5.66%
Psychological Abuse: 3 people, 5.66%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 3 people, 5.66%
Depression: 3 people, 5.66%
Suicide Attempt: 2 people, 3.77%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 3.77%
Drug Abuse: 2 people, 3.77%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 3.77%

* Approximation only. Some reports may have incomplete information.

Do you take Methylphenidate and have Coma?

- Check whether Coma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methylphenidate:

Methylphenidate (8,216 reports)

Coma treatments and more:

Coma (57,420 reports)

Browse all side effects of Methylphenidate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Coma:

Coma (2,785 drugs)

Browse all the conditions that are associated with Coma:

Coma (3,207 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate (the active ingredients of Methylphenidate) and Methylphenidate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.