Methylphenidate and Crying - a phase IV clinical study of FDA data

Summary:

Crying is reported as a side effect among people who take Methylphenidate (methylphenidate), especially for people who are male, 2-9 old, have been taking the drug for < 1 month also take Lisdexamfetamine Dimesylate, and have Attention deficit hyperactivity disorder.

The phase IV clinical study analyzes which people have Crying when taking Methylphenidate. It is created by eHealthMe based on reports of 8,120 people who have side effects when taking Methylphenidate from the FDA, and is updated regularly.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,213 Methylphenidate users. Check the latest studies of Methylphenidate.

What is Crying?

Crying is found to be associated with 1,514 drugs and 1,793 conditions by eHealthMe. Check the latest studies of Crying.

On Oct, 23, 2025

8,120 people reported to have side effects when taking Methylphenidate.
Among them, 59 people (0.73%) have Crying.

Among these 59 people:

How long have people been on Methylphenidate when they have Crying? *

What is the gender of people who have Crying when taking Methylphenidate? *

female: 48.15 %
male: 51.85 %

What is the age of people who have Crying when taking Methylphenidate? *

What are other drugs people take besides Methylphenidate? *

Zopiclone: 6 people, 10.17%
Lisdexamfetamine Dimesylate: 6 people, 10.17%
Magnesium: 5 people, 8.47%
Xyrem: 5 people, 8.47%
Clonazepam: 4 people, 6.78%
Vitamin D3: 4 people, 6.78%
Ritalin: 4 people, 6.78%
Cymbalta: 3 people, 5.08%
Divalproex Sodium: 3 people, 5.08%
Effexor: 3 people, 5.08%

What are other side effects people have besides Crying? *

Stress And Anxiety: 37 people, 62.71%
Fatigue (feeling of tiredness): 34 people, 57.63%
Insomnia (sleeplessness): 34 people, 57.63%
Suicidal Ideation: 34 people, 57.63%
Sleep Disorder: 33 people, 55.93%
Irritability: 31 people, 52.54%
Mood Swings (an extreme or rapid change in mood): 29 people, 49.15%
Depressed Mood: 28 people, 47.46%
Psychomotor Hyperactivity (feelings of extreme restlessness): 28 people, 47.46%
Speech Disorder: 27 people, 45.76%

What are the existing conditions these people have? *

Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 16 people, 27.12%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 10.17%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 10.17%
Drowsiness: 4 people, 6.78%
Depression: 4 people, 6.78%
Affective Disorder (mental disorder): 3 people, 5.08%
Stress And Anxiety: 3 people, 5.08%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 3.39%
Otitis Externa (external ear infection): 2 people, 3.39%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 2 people, 3.39%

* Approximation only. Some reports may have incomplete information.

Do you take Methylphenidate and have Crying?

- Check whether Crying is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methylphenidate:

Methylphenidate (8,213 reports)

Crying treatments and more:

Crying (43,771 reports)

Browse all side effects of Methylphenidate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Crying:

Crying (1,514 drugs)

Browse all the conditions that are associated with Crying:

Crying (1,793 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate (the active ingredients of Methylphenidate) and Methylphenidate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.