Methylphenidate and Epilepsy - a phase IV clinical study of FDA data

Summary:

Epilepsy is reported as a side effect among people who take Methylphenidate (methylphenidate), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Epilepsy when taking Methylphenidate. It is created by eHealthMe based on reports of 8,120 people who have side effects when taking Methylphenidate from the FDA, and is updated regularly.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,216 Methylphenidate users. Check the latest studies of Methylphenidate.

What is Epilepsy?

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures) is found to be associated with 1,164 drugs and 1,776 conditions by eHealthMe. Check the latest studies of Epilepsy.

On Jul, 06, 2026

8,120 people reported to have side effects when taking Methylphenidate.
Among them, 22 people (0.27%) have Epilepsy.

Among these 22 people:

How long have people been on Methylphenidate when they have Epilepsy? *

What is the gender of people who have Epilepsy when taking Methylphenidate? *

female: 88.24 %
male: 11.76 %

What is the age of people who have Epilepsy when taking Methylphenidate? *

What are other drugs people take besides Methylphenidate? *

What are other side effects people have besides Epilepsy? *

Haemorrhagic Stroke (stroke caused by the rupture of a blood vessel in the brain): 4 people, 18.18%
Aneurysm Ruptured (expansion of the aneurysm reaches a point where the wall becomes too thin, the aneurysm will rupture): 4 people, 18.18%
Hospitalisation: 4 people, 18.18%
Musculoskeletal Disorder (disease of the body's muscles, joints, tendons, ligaments and nerves): 3 people, 13.64%
Sleep Apnea Syndrome: 3 people, 13.64%
Adjustment Disorder With Depressed Mood: 2 people, 9.09%
Eye Movements - Uncontrollable: 2 people, 9.09%
Bruxism (habitual grinding of the teeth, typically during sleep): 2 people, 9.09%
Brain Neoplasm (tumour of brain): 2 people, 9.09%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 9.09%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 31.82%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 5 people, 22.73%
Affective Disorder (mental disorder): 2 people, 9.09%
Apathy: 2 people, 9.09%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 9.09%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 9.09%
Stress And Anxiety: 1 person, 4.55%
Indigestion: 1 person, 4.55%
High Blood Pressure: 1 person, 4.55%
High Blood Cholesterol: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Methylphenidate and have Epilepsy?

- Check whether Epilepsy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methylphenidate:

Methylphenidate (8,216 reports)

Epilepsy treatments and more:

Epilepsy (129,285 reports)

Browse all side effects of Methylphenidate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Epilepsy:

Epilepsy (1,164 drugs)

Browse all the conditions that are associated with Epilepsy:

Epilepsy (1,776 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate (the active ingredients of Methylphenidate) and Methylphenidate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.