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Methylphenidate and Hearing loss - a phase IV clinical study of FDA data

Summary:

Hearing loss is reported as a side effect among people who take Methylphenidate (methylphenidate), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Xyrem, and have Cataplexy.

The phase IV clinical study analyzes which people have Hearing loss when taking Methylphenidate. It is created by eHealthMe based on reports of 8,120 people who have side effects when taking Methylphenidate from the FDA, and is updated regularly.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,216 Methylphenidate users. Check the latest studies of Methylphenidate.

What is Hearing loss?

Hearing loss is found to be associated with 1,352 drugs and 2,378 conditions by eHealthMe. Check the latest studies of Hearing loss.

On Jul, 12, 2026

8,120 people reported to have side effects when taking Methylphenidate.
Among them, 16 people (0.2%) have Hearing loss.

Could Methylphenidate cause Hearing loss?

Among these 16 people:

How long have people been on Methylphenidate when they have Hearing loss? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hearing loss when taking Methylphenidate? *

  • female: 66.67 %
  • male: 33.33 %

What is the age of people who have Hearing loss when taking Methylphenidate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 10 %
  • 50-59: 40 %
  • 60+: 50 %

What are other drugs people take besides Methylphenidate? *

  1. Vitamin D3: 6 people, 37.50%
  2. Xyrem: 6 people, 37.50%
  3. Galafold: 4 people, 25.00%
  4. Furosemide: 3 people, 18.75%
  5. Estradiol: 3 people, 18.75%
  6. Spironolactone: 3 people, 18.75%
  7. Levothyroxine Sodium: 3 people, 18.75%
  8. Potassium Chloride: 3 people, 18.75%
  9. Cymbalta: 2 people, 12.50%
  10. Lamictal: 2 people, 12.50%

What are other side effects people have besides Hearing loss? *

  1. Tinnitus (a ringing in the ears): 7 people, 43.75%
  2. Weight Increased: 4 people, 25.00%
  3. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 4 people, 25.00%
  4. Malaise (a feeling of general discomfort or uneasiness): 4 people, 25.00%
  5. Anaemia (lack of blood): 4 people, 25.00%
  6. Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 25.00%
  7. Stress And Anxiety: 4 people, 25.00%
  8. Immunisation Reaction: 3 people, 18.75%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 18.75%
  10. Lymphatic Disorder (disease of lymphatic system): 3 people, 18.75%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 37.50%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 37.50%
  3. Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 4 people, 25.00%
  4. Pain: 2 people, 12.50%
  5. Cough: 2 people, 12.50%
  6. Dyspnea (difficult or laboured breathing): 1 person, 6.25%
  7. Arrhythmia Supraventricular (irregular heartbeat supraventricular origin): 1 person, 6.25%
  8. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 6.25%
  9. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 1 person, 6.25%
  10. Cardiac Failure Congestive: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Methylphenidate and have Hearing loss?

- Check whether Hearing loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methylphenidate:

Hearing loss treatments and more:

How severe was Hearing loss and when was it recovered:

Expand to all the drugs that have ingredients of methylphenidate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methylphenidate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hearing loss:

Browse all the conditions that are associated with Hearing loss:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate (the active ingredients of Methylphenidate) and Methylphenidate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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