Methylprednisolone and Type i hypersensitivity - a phase IV clinical study of FDA data

Summary:

Type i hypersensitivity is reported as a side effect among people who take Methylprednisolone (methylprednisolone), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Oxaliplatin, and have Immune tolerance induction.

The phase IV clinical study analyzes which people have Type i hypersensitivity when taking Methylprednisolone. It is created by eHealthMe based on reports of 58,374 people who have side effects when taking Methylprednisolone from the FDA, and is updated regularly.

What is Methylprednisolone?

Methylprednisolone has active ingredients of methylprednisolone. It is often used in inflammation. eHealthMe is studying from 59,645 Methylprednisolone users. Check the latest studies of Methylprednisolone.

What is Type i hypersensitivity?

Type i hypersensitivity is found to be associated with 136 drugs and 306 conditions by eHealthMe. Check the latest studies of Type i hypersensitivity.



On Jul, 15, 2026

58,374 people reported to have side effects when taking Methylprednisolone.
Among them, 29 people (0.05%) have Type i hypersensitivity.

Could Methylprednisolone cause Type i hypersensitivity?

Among these 29 people:

How long have people been on Methylprednisolone when they have Type i hypersensitivity? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Type i hypersensitivity when taking Methylprednisolone? *

  • female: 62.07 %
  • male: 37.93 %

What is the age of people who have Type i hypersensitivity when taking Methylprednisolone? *

  • 0-1: 0.0 %
  • 2-9: 3.85 %
  • 10-19: 7.69 %
  • 20-29: 23.08 %
  • 30-39: 11.54 %
  • 40-49: 26.92 %
  • 50-59: 7.69 %
  • 60+: 19.23 %

What are other drugs people take besides Methylprednisolone? *

  1. Oxaliplatin: 5 people, 17.24%
  2. Famotidine: 4 people, 13.79%
  3. Hydrocortisone: 4 people, 13.79%
  4. Prednisolone: 4 people, 13.79%
  5. Ranitidine: 4 people, 13.79%
  6. Isoniazid: 3 people, 10.34%
  7. Propofol: 3 people, 10.34%
  8. Dexamethasone: 3 people, 10.34%
  9. Ondansetron: 3 people, 10.34%
  10. Acetaminophen: 3 people, 10.34%

What are other side effects people have besides Type i hypersensitivity? *

  1. Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 8 people, 27.59%
  2. Skin Reaction: 3 people, 10.34%
  3. Skin Blushing/flushing (a sudden reddening of the face, neck): 3 people, 10.34%
  4. Dyspnea (difficult or laboured breathing): 3 people, 10.34%
  5. Hypotension (abnormally low blood pressure): 3 people, 10.34%
  6. Throat Tightness: 2 people, 6.90%
  7. Drug Hypersensitivity: 2 people, 6.90%
  8. Drug Intolerance (drug sensitivity): 2 people, 6.90%
  9. Skin Test Positive: 2 people, 6.90%
  10. Drug Ineffective: 2 people, 6.90%

What are the existing conditions these people have? *

  1. Immune Tolerance Induction: 3 people, 10.34%
  2. Anaesthesia: 2 people, 6.90%
  3. Transplant Rejection (a transplant material is not worked): 2 people, 6.90%
  4. Neoplasm Malignant (cancer tumour): 2 people, 6.90%
  5. Meningitis Tuberculous (a bacterial infection of the membranes covering the brain and spinal cord (meninges)): 2 people, 6.90%
  6. Drug Hypersensitivity: 2 people, 6.90%
  7. Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 2 people, 6.90%
  8. Vitritis (inflammation of the vitreous humour of the eye): 1 person, 3.45%
  9. Gestational Trophoblastic Disease (disease of foetus surrounding during pregnancy): 1 person, 3.45%
  10. Asthma: 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Methylprednisolone and have Type i hypersensitivity?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methylprednisolone:

Type i hypersensitivity treatments and more:

How severe was Type i hypersensitivity and when was it recovered:

Expand to all the drugs that have ingredients of methylprednisolone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methylprednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Type i hypersensitivity:

Browse all the conditions that are associated with Type i hypersensitivity:


How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone (the active ingredients of Methylprednisolone) and Methylprednisolone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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