Metoprolol succinate and Diverticular perforation - a phase IV clinical study of FDA data

Summary:

Diverticular perforation is reported as a side effect among people who take Metoprolol succinate (metoprolol succinate), especially for people who are male, 60+ old, also take Cellcept, and have Diarrhea.

The phase IV clinical study analyzes which people have Diverticular perforation when taking Metoprolol succinate. It is created by eHealthMe based on reports of 64,247 people who have side effects when taking Metoprolol succinate from the FDA, and is updated regularly.

What is Metoprolol succinate?

Metoprolol succinate has active ingredients of metoprolol succinate. It is often used in high blood pressure. eHealthMe is studying from 66,933 Metoprolol succinate users. Check the latest studies of Metoprolol succinate.

What is Diverticular perforation?

Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated) is found to be associated with 365 drugs and 413 conditions by eHealthMe. Check the latest studies of Diverticular perforation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

64,247 people reported to have side effects when taking Metoprolol succinate.
Among them, 18 people (0.03%) have Diverticular perforation.

Could Metoprolol succinate cause Diverticular perforation?

Among these 18 people:

What is the gender of people who have Diverticular perforation when taking Metoprolol succinate? *

female: 38.89 %
male: 61.11 %

What is the age of people who have Diverticular perforation when taking Metoprolol succinate? *

What are other drugs people take besides Metoprolol succinate? *

Colecalciferol: 8 people, 44.44%
Cellcept: 8 people, 44.44%
Cabozantinib: 3 people, 16.67%
Zofran: 2 people, 11.11%
Isosorbide Mononitrate: 2 people, 11.11%
Imodium: 2 people, 11.11%
Fluconazole: 2 people, 11.11%
Eliquis: 2 people, 11.11%
Dyazide: 2 people, 11.11%
Copaxone: 2 people, 11.11%

What are other side effects people have besides Diverticular perforation? *

Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 8 people, 44.44%
Colitis (inflammation of colon): 3 people, 16.67%
Peridiverticular Abscess: 2 people, 11.11%
Diarrhea: 2 people, 11.11%
Vesical Fistula (a fistulous passage from the urinary bladder): 1 person, 5.56%
Dyspnea (difficult or laboured breathing): 1 person, 5.56%
Abscess (pus): 1 person, 5.56%
Autoimmune Hepatitis: 1 person, 5.56%
Confusion: 1 person, 5.56%
Confusional State: 1 person, 5.56%

What are the existing conditions these people have? *

Urinary Tract Infection: 3 people, 16.67%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 16.67%
Diarrhea: 3 people, 16.67%
Dizziness: 2 people, 11.11%
Sinus Disorder (disease of sinus): 2 people, 11.11%
Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 2 people, 11.11%
Nausea (feeling of having an urge to vomit): 2 people, 11.11%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 11.11%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 11.11%
Multiple Myeloma (cancer of the plasma cells): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Metoprolol succinate and have Diverticular perforation?

- Check whether Diverticular perforation is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metoprolol succinate:

Metoprolol succinate (66,933 reports)

Browse all side effects of Metoprolol succinate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diverticular perforation:

Diverticular perforation (365 drugs)

Browse all the conditions that are associated with Diverticular perforation:

Diverticular perforation (413 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metoprolol succinate (the active ingredients of Metoprolol succinate) and Metoprolol succinate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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