Mexitil and Pleural effusion - a phase IV clinical study of FDA data

Summary:

Pleural effusion is reported as a side effect among people who take Mexitil (mexiletine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Lasix, and have Lupus nephritis.

The phase IV clinical study analyzes which people have Pleural effusion when taking Mexitil. It is created by eHealthMe based on reports of 1,881 people who have side effects when taking Mexitil from the FDA, and is updated regularly.

What is Mexitil?

Mexitil has active ingredients of mexiletine hydrochloride. eHealthMe is studying from 1,893 Mexitil users. Check the latest studies of Mexitil.

What is Pleural effusion?

Pleural effusion (water on the lungs) is found to be associated with 2,223 drugs and 3,144 conditions by eHealthMe. Check the latest studies of Pleural effusion.

On Jul, 12, 2026

1,881 people reported to have side effects when taking Mexitil.
Among them, 36 people (1.91%) have Pleural effusion.

Among these 36 people:

How long have people been on Mexitil when they have Pleural effusion? *

What is the gender of people who have Pleural effusion when taking Mexitil? *

female: 11.11 %
male: 88.89 %

What is the age of people who have Pleural effusion when taking Mexitil? *

What are other drugs people take besides Mexitil? *

What are other side effects people have besides Pleural effusion? *

Generalised Oedema (swelling all over the body): 10 people, 27.78%
Fever: 10 people, 27.78%
Diarrhea: 9 people, 25.00%
Cardiac Failure: 9 people, 25.00%
Dyspnea (difficult or laboured breathing): 9 people, 25.00%
Mitral Valve Incompetence (inefficient heart valve): 7 people, 19.44%
Urinary Retention (the inability to completely or partially empty the bladder): 7 people, 19.44%
Anaemia (lack of blood): 7 people, 19.44%
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 6 people, 16.67%
Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 6 people, 16.67%

What are the existing conditions these people have? *

Pain: 5 people, 13.89%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 5 people, 13.89%
Multiple Myeloma (cancer of the plasma cells): 4 people, 11.11%
Renal Cell Carcinoma (a kidney cancer): 4 people, 11.11%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 3 people, 8.33%
Arrhythmias (irregular heartbeat): 3 people, 8.33%
Bile Duct Cancer Stage Iii: 3 people, 8.33%
High Blood Pressure: 3 people, 8.33%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 8.33%
Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 3 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Mexitil and have Pleural effusion?

- Check whether Pleural effusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mexitil:

Mexitil (1,893 reports)

Pleural effusion treatments and more:

Pleural effusion (84,634 reports)

Browse all side effects of Mexitil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pleural effusion:

Pleural effusion (2,223 drugs)

Browse all the conditions that are associated with Pleural effusion:

Pleural effusion (3,144 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mexiletine hydrochloride (the active ingredients of Mexitil) and Mexitil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.