Microzide and Oedema peripheral - a phase IV clinical study of FDA data

Summary:

Oedema peripheral is reported as a side effect among people who take Microzide (hydrochlorothiazide), especially for people who are female, 40-49 old, also take Vioxx, and have Hypotension.

The phase IV clinical study analyzes which people have Oedema peripheral when taking Microzide. It is created by eHealthMe based on reports of 946 people who have side effects when taking Microzide from the FDA, and is updated regularly.

What is Microzide?

Microzide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 994 Microzide users. Check the latest studies of Microzide.

What is Oedema peripheral?

Oedema peripheral (superficial swelling) is found to be associated with 2,774 drugs and 3,465 conditions by eHealthMe. Check the latest studies of Oedema peripheral.

On Jul, 27, 2026

946 people reported to have side effects when taking Microzide.
Among them, 16 people (1.69%) have Oedema peripheral.

Could Microzide cause Oedema peripheral?

Among these 16 people:

What is the gender of people who have Oedema peripheral when taking Microzide? *

female: 81.25 %
male: 18.75 %

What is the age of people who have Oedema peripheral when taking Microzide? *

What are other drugs people take besides Microzide? *

What are other side effects people have besides Oedema peripheral? *

Acute Kidney Failure: 8 people, 50.00%
Drug Ineffective: 7 people, 43.75%
Sleep Disorder: 6 people, 37.50%
Malaise (a feeling of general discomfort or uneasiness): 6 people, 37.50%
Diarrhea: 6 people, 37.50%
Weight Increased: 5 people, 31.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 31.25%
Nausea (feeling of having an urge to vomit): 5 people, 31.25%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 31.25%
Pain: 5 people, 31.25%

What are the existing conditions these people have? *

Muscle Spasms (muscle contraction): 4 people, 25.00%
Immunodeficiency Disorders: 4 people, 25.00%
Dry Skin: 4 people, 25.00%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 25.00%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 25.00%
Hypotension (abnormally low blood pressure): 4 people, 25.00%
Back Pain: 3 people, 18.75%
Oedema (fluid collection in tissue): 1 person, 6.25%
Neuropathy Peripheral (surface nerve damage): 1 person, 6.25%
Urinary Tract Infection: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Microzide and have Oedema peripheral?

- Check whether Oedema peripheral is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Microzide:

Microzide (994 reports)

Oedema peripheral treatments and more:

Oedema peripheral (172,690 reports)

Browse all side effects of Microzide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oedema peripheral:

Oedema peripheral (2,774 drugs)

Browse all the conditions that are associated with Oedema peripheral:

Oedema peripheral (3,465 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Microzide) and Microzide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.