Midodrine hydrochloride and Chills - a phase IV clinical study of FDA data

Summary:

Chills is reported as a side effect among people who take Midodrine hydrochloride (midodrine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Chills when taking Midodrine hydrochloride. It is created by eHealthMe based on reports of 3,007 people who have side effects when taking Midodrine hydrochloride from the FDA, and is updated regularly.

What is Midodrine hydrochloride?

Midodrine hydrochloride has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 3,274 Midodrine hydrochloride users. Check the latest studies of Midodrine hydrochloride.

What is Chills?

Chills (felling of cold) is found to be associated with 2,551 drugs and 3,475 conditions by eHealthMe. Check the latest studies of Chills.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

3,007 people reported to have side effects when taking Midodrine hydrochloride.
Among them, 45 people (1.5%) have Chills.

Could Midodrine hydrochloride cause Chills?

Among these 45 people:

How long have people been on Midodrine hydrochloride when they have Chills? *

What is the gender of people who have Chills when taking Midodrine hydrochloride? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Chills when taking Midodrine hydrochloride? *

What are other drugs people take besides Midodrine hydrochloride? *

What are other side effects people have besides Chills? *

Nausea (feeling of having an urge to vomit): 26 people, 57.78%
Fever: 21 people, 46.67%
Headache (pain in head): 17 people, 37.78%
Chest Pain: 16 people, 35.56%
Dizziness: 14 people, 31.11%
Dyspnea (difficult or laboured breathing): 14 people, 31.11%
Pain: 12 people, 26.67%
Nausea And Vomiting: 11 people, 24.44%
Fatigue (feeling of tiredness): 11 people, 24.44%
Diarrhea: 11 people, 24.44%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 13.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 11.11%
Stress And Anxiety: 2 people, 4.44%
Agitated Depression: 2 people, 4.44%
Asthma: 2 people, 4.44%
Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 2 people, 4.44%
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 2 people, 4.44%
Cardiac Failure Chronic: 2 people, 4.44%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 2 people, 4.44%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 4.44%

* Approximation only. Some reports may have incomplete information.

Do you take Midodrine hydrochloride and have Chills?

- Check whether Chills is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Midodrine hydrochloride:

Midodrine hydrochloride (3,274 reports)

Chills treatments and more:

Chills (145,628 reports)

Browse all side effects of Midodrine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chills:

Chills (2,551 drugs)

Browse all the conditions that are associated with Chills:

Chills (3,475 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on midodrine hydrochloride (the active ingredients of Midodrine hydrochloride) and Midodrine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.