Midodrine hydrochloride and Hyperhidrosis - a phase IV clinical study of FDA data

Summary:

Hyperhidrosis is reported as a side effect among people who take Midodrine hydrochloride (midodrine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Hyperhidrosis when taking Midodrine hydrochloride. It is created by eHealthMe based on reports of 3,007 people who have side effects when taking Midodrine hydrochloride from the FDA, and is updated regularly.

What is Midodrine hydrochloride?

Midodrine hydrochloride has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 3,274 Midodrine hydrochloride users. Check the latest studies of Midodrine hydrochloride.

What is Hyperhidrosis?

Hyperhidrosis (abnormally increased sweating) is found to be associated with 2,551 drugs and 3,546 conditions by eHealthMe. Check the latest studies of Hyperhidrosis.

On Jul, 15, 2026

3,007 people reported to have side effects when taking Midodrine hydrochloride.
Among them, 42 people (1.4%) have Hyperhidrosis.

Could Midodrine hydrochloride cause Hyperhidrosis?

Among these 42 people:

How long have people been on Midodrine hydrochloride when they have Hyperhidrosis? *

What is the gender of people who have Hyperhidrosis when taking Midodrine hydrochloride? *

female: 52.38 %
male: 47.62 %

What is the age of people who have Hyperhidrosis when taking Midodrine hydrochloride? *

What are other drugs people take besides Midodrine hydrochloride? *

Acetaminophen: 17 people, 40.48%
Omeprazole: 13 people, 30.95%
Aspirin: 13 people, 30.95%
Citalopram Hydrobromide: 9 people, 21.43%
Gabapentin: 8 people, 19.05%
Furosemide: 8 people, 19.05%
Ondansetron: 7 people, 16.67%
Sodium Chloride: 7 people, 16.67%
Vitamin D3: 6 people, 14.29%
Levothyroxine Sodium: 6 people, 14.29%

What are other side effects people have besides Hyperhidrosis? *

Nausea (feeling of having an urge to vomit): 14 people, 33.33%
Dizziness: 12 people, 28.57%
Dyspnea (difficult or laboured breathing): 12 people, 28.57%
Chest Pain: 10 people, 23.81%
Weakness: 9 people, 21.43%
Headache (pain in head): 9 people, 21.43%
Nausea And Vomiting: 9 people, 21.43%
Fatigue (feeling of tiredness): 9 people, 21.43%
Back Pain: 8 people, 19.05%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 16.67%

What are the existing conditions these people have? *

Parkinson's Disease: 7 people, 16.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 14.29%
Pain: 5 people, 11.90%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 9.52%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 7.14%
Insomnia (sleeplessness): 2 people, 4.76%
Asthma: 2 people, 4.76%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 2 people, 4.76%
Fever: 2 people, 4.76%
Infection: 2 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Midodrine hydrochloride and have Hyperhidrosis?

- Check whether Hyperhidrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Midodrine hydrochloride:

Midodrine hydrochloride (3,274 reports)

Hyperhidrosis treatments and more:

Hyperhidrosis (147,206 reports)

Browse all side effects of Midodrine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperhidrosis:

Hyperhidrosis (2,551 drugs)

Browse all the conditions that are associated with Hyperhidrosis:

Hyperhidrosis (3,546 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on midodrine hydrochloride (the active ingredients of Midodrine hydrochloride) and Midodrine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.