Midodrine hydrochloride and Sleep terror - a phase IV clinical study of FDA data

Summary:

Sleep terror is reported as a side effect among people who take Midodrine hydrochloride (midodrine hydrochloride), especially for people who are male, 60+ old, also take Lipitor, and have Prostate cancer.

The phase IV clinical study analyzes which people have Sleep terror when taking Midodrine hydrochloride. It is created by eHealthMe based on reports of 3,007 people who have side effects when taking Midodrine hydrochloride from the FDA, and is updated regularly.

What is Midodrine hydrochloride?

Midodrine hydrochloride has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 3,274 Midodrine hydrochloride users. Check the latest studies of Midodrine hydrochloride.

What is Sleep terror?

Sleep terror (felling of terror in sleep) is found to be associated with 303 drugs and 386 conditions by eHealthMe. Check the latest studies of Sleep terror.



On Aug, 11, 2026

3,007 people reported to have side effects when taking Midodrine hydrochloride.
Among them, 16 people (0.53%) have Sleep terror.

Could Midodrine hydrochloride cause Sleep terror?

Among these 16 people:

What is the gender of people who have Sleep terror when taking Midodrine hydrochloride? *

  • female: 0.0 %
  • male: 100 %

What is the age of people who have Sleep terror when taking Midodrine hydrochloride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 6.25 %
  • 60+: 93.75 %

What are other drugs people take besides Midodrine hydrochloride? *

  1. Zometa: 16 people, 100.00%
  2. Proscar: 16 people, 100.00%
  3. Aromasin: 16 people, 100.00%
  4. Casodex: 16 people, 100.00%
  5. Effexor: 16 people, 100.00%
  6. Florinef: 16 people, 100.00%
  7. Hyzaar: 16 people, 100.00%
  8. Ibuprofen: 16 people, 100.00%
  9. Lexapro: 16 people, 100.00%
  10. Lipitor: 16 people, 100.00%

What are other side effects people have besides Sleep terror? *

  1. Joint Pain: 16 people, 100.00%
  2. Lung Infection: 16 people, 100.00%
  3. Osteoporosis (bones weak and more likely to break): 16 people, 100.00%
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 16 people, 100.00%
  5. Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 16 people, 100.00%
  6. Neck Pain: 16 people, 100.00%
  7. Metastases To Lymph Nodes (cancer spreads to lymph node): 16 people, 100.00%
  8. Confusional State: 16 people, 100.00%
  9. Metastases To Bone (cancer spreads to bone): 16 people, 100.00%
  10. Depression: 16 people, 100.00%

What are the existing conditions these people have? *

  1. Prostate Cancer: 16 people, 100.00%
  2. Bone Density Abnormal: 15 people, 93.75%
  3. Pain: 14 people, 87.50%

* Approximation only. Some reports may have incomplete information.

Do you take Midodrine hydrochloride and have Sleep terror?

- Check whether Sleep terror is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Midodrine hydrochloride:

Sleep terror treatments and more:

How severe was Sleep terror and when was it recovered:

Expand to all the drugs that have ingredients of midodrine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Midodrine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sleep terror:

Browse all the conditions that are associated with Sleep terror:


How the study uses the data?

The study uses data from the FDA. It is based on midodrine hydrochloride (the active ingredients of Midodrine hydrochloride) and Midodrine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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