Migranal and Insomnia - a phase IV clinical study of FDA data

Summary:

Insomnia is reported as a side effect among people who take Migranal (dihydroergotamine mesylate), especially for people who are female, 50-59 old, have been taking the drug for 10+ years also take Prozac, and have Depression.

The phase IV clinical study analyzes which people have Insomnia when taking Migranal. It is created by eHealthMe based on reports of 531 people who have side effects when taking Migranal from the FDA, and is updated regularly.

What is Migranal?

Migranal has active ingredients of dihydroergotamine mesylate. It is often used in migraine. eHealthMe is studying from 560 Migranal users. Check the latest studies of Migranal.

What is Insomnia?

Insomnia (sleeplessness) is found to be associated with 3,115 drugs and 5,174 conditions by eHealthMe. Check the latest studies of Insomnia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

531 people reported to have side effects when taking Migranal.
Among them, 13 people (2.45%) have Insomnia.

Among these 13 people:

How long have people been on Migranal when they have Insomnia? *

What is the gender of people who have Insomnia when taking Migranal? *

female: 92.31 %
male: 7.69 %

What is the age of people who have Insomnia when taking Migranal? *

What are other drugs people take besides Migranal? *

What are other side effects people have besides Insomnia? *

Pain: 8 people, 61.54%
Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 53.85%
Dizziness: 7 people, 53.85%
Stress And Anxiety: 7 people, 53.85%
Fatigue (feeling of tiredness): 7 people, 53.85%
Headache (pain in head): 7 people, 53.85%
Memory Loss: 6 people, 46.15%
Abdominal Pain: 6 people, 46.15%
Depression: 6 people, 46.15%
Feeling Abnormal: 6 people, 46.15%

What are the existing conditions these people have? *

Pain: 7 people, 53.85%
Depression: 7 people, 53.85%
Sleep Disorder: 6 people, 46.15%
Upper Respiratory Tract Infection: 4 people, 30.77%
Muscle Spasms (muscle contraction): 4 people, 30.77%
Mood Swings (an extreme or rapid change in mood): 4 people, 30.77%
Dyspnea (difficult or laboured breathing): 4 people, 30.77%
Osteoporosis (bones weak and more likely to break): 2 people, 15.38%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 15.38%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Migranal and have Insomnia?

- Check whether Insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Migranal:

Migranal (560 reports)

Insomnia treatments and more:

Insomnia (438,087 reports)

Browse all side effects of Migranal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia:

Insomnia (3,115 drugs)

Browse all the conditions that are associated with Insomnia:

Insomnia (5,174 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dihydroergotamine mesylate (the active ingredients of Migranal) and Migranal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.