Mirena and Thyroid cancer - a phase IV clinical study of FDA data

Summary:

Thyroid cancer is reported as a side effect among people who take Mirena (levonorgestrel), especially for people who are female, 40-49 old, have been taking the drug for 1 - 2 years also take Levothyroxine Sodium, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Thyroid cancer when taking Mirena. It is created by eHealthMe based on reports of 143,466 people who have side effects when taking Mirena from the FDA, and is updated regularly.

What is Mirena?

Mirena has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 145,266 Mirena users. Check the latest studies of Mirena.

What is Thyroid cancer?

Thyroid cancer is found to be associated with 599 drugs and 839 conditions by eHealthMe. Check the latest studies of Thyroid cancer.

On Jul, 02, 2026

143,466 people reported to have side effects when taking Mirena.
Among them, 31 people (0.02%) have Thyroid cancer.

Among these 31 people:

How long have people been on Mirena when they have Thyroid cancer? *

What is the gender of people who have Thyroid cancer when taking Mirena? *

female: 100 %
male: 0.0 %

What is the age of people who have Thyroid cancer when taking Mirena? *

What are other drugs people take besides Mirena? *

What are other side effects people have besides Thyroid cancer? *

Weakness: 4 people, 12.90%
Dizziness: 4 people, 12.90%
Fatigue (feeling of tiredness): 3 people, 9.68%
Migraine (headache): 3 people, 9.68%
Abdominal Pain Lower: 3 people, 9.68%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 9.68%
Vision Blurred: 3 people, 9.68%
Headache (pain in head): 3 people, 9.68%
Dyspnea (difficult or laboured breathing): 3 people, 9.68%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2 people, 6.45%

What are the existing conditions these people have? *

Menstrual Disorder (disease of menstrual cycle): 3 people, 9.68%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 9.68%
Venous Insufficiency (poor circulation of blood caused by damaged or enlarged veins): 1 person, 3.23%
Type 2 Diabetes: 1 person, 3.23%
Swelling: 1 person, 3.23%
Pain: 1 person, 3.23%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 3.23%
High Blood Pressure: 1 person, 3.23%
High Blood Cholesterol: 1 person, 3.23%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Mirena and have Thyroid cancer?

- Check whether Thyroid cancer is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mirena:

Mirena (145,266 reports)

Thyroid cancer treatments and more:

Thyroid cancer (24,392 reports)

Browse all side effects of Mirena:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroid cancer:

Thyroid cancer (599 drugs)

Browse all the conditions that are associated with Thyroid cancer:

Thyroid cancer (839 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on levonorgestrel (the active ingredients of Mirena) and Mirena (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.