Mirtazapine and Endocarditis - a phase IV clinical study of FDA data

Summary:

Endocarditis is reported as a side effect among people who take Mirtazapine (mirtazapine), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Pantoprazole, and have Tumor lysis syndrome.

The phase IV clinical study analyzes which people have Endocarditis when taking Mirtazapine. It is created by eHealthMe based on reports of 79,492 people who have side effects when taking Mirtazapine from the FDA, and is updated regularly.

What is Mirtazapine?

Mirtazapine has active ingredients of mirtazapine. It is often used in depression. eHealthMe is studying from 82,120 Mirtazapine users. Check the latest studies of Mirtazapine.

What is Endocarditis?

Endocarditis (inflammation in heart muscle) is found to be associated with 648 drugs and 824 conditions by eHealthMe. Check the latest studies of Endocarditis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 22, 2026

79,492 people reported to have side effects when taking Mirtazapine.
Among them, 36 people (0.05%) have Endocarditis.

Could Mirtazapine cause Endocarditis?

Among these 36 people:

How long have people been on Mirtazapine when they have Endocarditis? *

  • < 1 month: 20 %
  • 1 - 6 months: 80 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Endocarditis when taking Mirtazapine? *

  • female: 54.55 %
  • male: 45.45 %

What is the age of people who have Endocarditis when taking Mirtazapine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 21.43 %
  • 40-49: 14.29 %
  • 50-59: 0.0 %
  • 60+: 64.29 %

What are other drugs people take besides Mirtazapine? *

  1. Pantoprazole: 8 people, 22.22%
  2. Methotrexate: 7 people, 19.44%
  3. Prilosec: 7 people, 19.44%
  4. Tylenol: 6 people, 16.67%
  5. Spironolactone: 6 people, 16.67%
  6. Folic Acid: 6 people, 16.67%
  7. Benadryl: 6 people, 16.67%
  8. Bactrim Ds: 6 people, 16.67%
  9. Metoprolol Tartrate: 6 people, 16.67%
  10. Novolin R: 5 people, 13.89%

What are other side effects people have besides Endocarditis? *

  1. Dyspnea (difficult or laboured breathing): 9 people, 25.00%
  2. Hypotension (abnormally low blood pressure): 8 people, 22.22%
  3. Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 19.44%
  4. Oedema Peripheral (superficial swelling): 6 people, 16.67%
  5. Acute Kidney Failure: 6 people, 16.67%
  6. Fever: 6 people, 16.67%
  7. Cough: 6 people, 16.67%
  8. Dehydration (dryness resulting from the removal of water): 6 people, 16.67%
  9. Hyperglycemia (high blood sugar): 5 people, 13.89%
  10. Haematoma (collection of blood outside the blood vessels): 5 people, 13.89%

What are the existing conditions these people have? *

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 13.89%
  2. Tumor Lysis Syndrome: 5 people, 13.89%
  3. Leukoencephalopathy (disease of the white matter in the brain): 4 people, 11.11%
  4. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 4 people, 11.11%
  5. Chronic Renal Failure (kidney failure): 4 people, 11.11%
  6. Reflux Oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus): 3 people, 8.33%
  7. High Blood Pressure: 3 people, 8.33%
  8. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 8.33%
  9. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 5.56%
  10. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Mirtazapine and have Endocarditis?

- Check whether Endocarditis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mirtazapine:

Endocarditis treatments and more:

How severe was Endocarditis and when was it recovered:

Expand to all the drugs that have ingredients of mirtazapine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mirtazapine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Endocarditis:

Browse all the conditions that are associated with Endocarditis:


How the study uses the data?

The study uses data from the FDA. It is based on mirtazapine (the active ingredients of Mirtazapine) and Mirtazapine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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