Misoprostol and Muscle aches - a phase IV clinical study of FDA data

Summary:

Muscle aches is reported as a side effect among people who take Misoprostol (misoprostol), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Methotrexate, and have Ill-defined disorder.

The phase IV clinical study analyzes which people have Muscle aches when taking Misoprostol. It is created by eHealthMe based on reports of 8,111 people who have side effects when taking Misoprostol from the FDA, and is updated regularly.

What is Misoprostol?

Misoprostol has active ingredients of misoprostol. It is often used in abortion. eHealthMe is studying from 8,222 Misoprostol users. Check the latest studies of Misoprostol.

What is Muscle aches?

Muscle aches (muscle pain) is found to be associated with 2,722 drugs and 3,745 conditions by eHealthMe. Check the latest studies of Muscle aches.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 24, 2026

8,111 people reported to have side effects when taking Misoprostol.
Among them, 33 people (0.41%) have Muscle aches.

Could Misoprostol cause Muscle aches?

Among these 33 people:

How long have people been on Misoprostol when they have Muscle aches? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Muscle aches when taking Misoprostol? *

  • female: 84.85 %
  • male: 15.15 %

What is the age of people who have Muscle aches when taking Misoprostol? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 27.59 %
  • 40-49: 17.24 %
  • 50-59: 17.24 %
  • 60+: 37.93 %

What are other drugs people take besides Misoprostol? *

  1. Methotrexate: 6 people, 18.18%
  2. Hydroxychloroquine Sulfate: 5 people, 15.15%
  3. Lipitor: 5 people, 15.15%
  4. Fosamax: 5 people, 15.15%
  5. Oxycodone And Acetaminophen: 5 people, 15.15%
  6. Actonel: 4 people, 12.12%
  7. Restasis: 4 people, 12.12%
  8. Lisinopril: 4 people, 12.12%
  9. Folic Acid: 4 people, 12.12%
  10. Levothyroxine Sodium: 3 people, 9.09%

What are other side effects people have besides Muscle aches? *

  1. Weakness: 9 people, 27.27%
  2. Joint Pain: 8 people, 24.24%
  3. Tremor (trembling or shaking movements in one or more parts of your body): 8 people, 24.24%
  4. Nausea And Vomiting: 7 people, 21.21%
  5. Diarrhea: 7 people, 21.21%
  6. Oral Pain: 7 people, 21.21%
  7. Glossodynia (a burning or painful sensation in the tongue): 7 people, 21.21%
  8. Hair Loss: 7 people, 21.21%
  9. Pain Of Skin: 7 people, 21.21%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 21.21%

What are the existing conditions these people have? *

  1. Ill-Defined Disorder: 5 people, 15.15%
  2. Osteoporosis (bones weak and more likely to break): 4 people, 12.12%
  3. High Blood Pressure: 4 people, 12.12%
  4. Psoriasis (immune-mediated disease that affects the skin): 2 people, 6.06%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 6.06%
  6. Gestational Hypertension (elevated blood pressure during pregnancy): 2 people, 6.06%
  7. High Blood Cholesterol: 2 people, 6.06%
  8. Hiv Infection: 1 person, 3.03%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 3.03%
  10. Back Disorder: 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Misoprostol and have Muscle aches?

- Check whether Muscle aches is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Misoprostol:

Muscle aches treatments and more:

How severe was Muscle aches and when was it recovered:

Expand to all the drugs that have ingredients of misoprostol:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Misoprostol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle aches:

Browse all the conditions that are associated with Muscle aches:


How the study uses the data?

The study uses data from the FDA. It is based on misoprostol (the active ingredients of Misoprostol) and Misoprostol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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