Mitoxantrone and Torsade de pointes - a phase IV clinical study of FDA data

Summary:

Torsade de pointes is reported as a side effect among people who take Mitoxantrone (mitoxantrone hydrochloride), especially for people who are female, 10-19 old, also take Cytarabine, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Torsade de pointes when taking Mitoxantrone. It is created by eHealthMe based on reports of 8,117 people who have side effects when taking Mitoxantrone from the FDA, and is updated regularly.

What is Mitoxantrone?

Mitoxantrone has active ingredients of mitoxantrone hydrochloride. eHealthMe is studying from 8,125 Mitoxantrone users. Check the latest studies of Mitoxantrone.

What is Torsade de pointes?

Torsade de pointes (a abnormal heart rate with abnormal beating pattern) is found to be associated with 558 drugs and 928 conditions by eHealthMe. Check the latest studies of Torsade de pointes.

On Jul, 15, 2026

8,117 people reported to have side effects when taking Mitoxantrone.
Among them, 12 people (0.15%) have Torsade de pointes.

Could Mitoxantrone cause Torsade de pointes?

Among these 12 people:

What is the gender of people who have Torsade de pointes when taking Mitoxantrone? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Torsade de pointes when taking Mitoxantrone? *

What are other drugs people take besides Mitoxantrone? *

What are other side effects people have besides Torsade de pointes? *

Fainting (loss of consciousness and postural tone): 3 people, 25.00%
Pulmonary Oedema (fluid accumulation in the lungs): 2 people, 16.67%
Electrocardiogram Qt Prolonged: 2 people, 16.67%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 2 people, 16.67%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 2 people, 16.67%
Hyperbilirubinaemia (excess of bilirubin in the blood): 2 people, 16.67%
Ejection Fraction Abnormal (abnormality in percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat): 2 people, 16.67%
Hypertriglyceridaemia (excess of triglycerides in the blood): 2 people, 16.67%
Cardiac Arrest: 2 people, 16.67%
Hypotension (abnormally low blood pressure): 2 people, 16.67%

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 33.33%
Systemic Candida (whole body fungal infection): 3 people, 25.00%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 25.00%
Febrile Neutropenia (fever with reduced white blood cells): 2 people, 16.67%
Acute Promyelocytic Leukaemia (cancer of the blood and bone marrow): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Mitoxantrone and have Torsade de pointes?

- Check whether Torsade de pointes is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mitoxantrone:

Mitoxantrone (8,125 reports)

Browse all side effects of Mitoxantrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Torsade de pointes:

Torsade de pointes (558 drugs)

Browse all the conditions that are associated with Torsade de pointes:

Torsade de pointes (928 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mitoxantrone hydrochloride (the active ingredients of Mitoxantrone) and Mitoxantrone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.