Mitoxantrone and Ventricular dysfunction - a phase IV clinical study of FDA data

Summary:

Ventricular dysfunction is reported as a side effect among people who take Mitoxantrone (mitoxantrone hydrochloride), especially for people who are female, 2-9 old, have been taking the drug for 1 - 6 months also take Ativan, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Ventricular dysfunction when taking Mitoxantrone. It is created by eHealthMe based on reports of 8,117 people who have side effects when taking Mitoxantrone from the FDA, and is updated regularly.

What is Mitoxantrone?

Mitoxantrone has active ingredients of mitoxantrone hydrochloride. eHealthMe is studying from 8,125 Mitoxantrone users. Check the latest studies of Mitoxantrone.

What is Ventricular dysfunction?

Ventricular dysfunction (heart dysfunction) is found to be associated with 450 drugs and 551 conditions by eHealthMe. Check the latest studies of Ventricular dysfunction.

On Aug, 11, 2026

8,117 people reported to have side effects when taking Mitoxantrone.
Among them, 11 people (0.14%) have Ventricular dysfunction.

Could Mitoxantrone cause Ventricular dysfunction?

Among these 11 people:

How long have people been on Mitoxantrone when they have Ventricular dysfunction? *

What is the gender of people who have Ventricular dysfunction when taking Mitoxantrone? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Ventricular dysfunction when taking Mitoxantrone? *

What are other drugs people take besides Mitoxantrone? *

What are other side effects people have besides Ventricular dysfunction? *

Cardiomyopathy (weakening of the heart muscle): 7 people, 63.64%
Cardiac Failure: 5 people, 45.45%
Dyspnea (difficult or laboured breathing): 4 people, 36.36%
Cardiotoxicity (damage to the heart muscle): 4 people, 36.36%
Ejection Fraction Decreased (systolic heart failure): 4 people, 36.36%
Hypoperfusion (decreased blood flow through an organ): 3 people, 27.27%
Urine Output Decreased: 3 people, 27.27%
Hepatic Function Abnormal: 3 people, 27.27%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 3 people, 27.27%
Hypotension (abnormally low blood pressure): 2 people, 18.18%

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 27.27%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 18.18%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 18.18%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Mitoxantrone and have Ventricular dysfunction?

- Check whether Ventricular dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mitoxantrone:

Mitoxantrone (8,125 reports)

Browse all side effects of Mitoxantrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ventricular dysfunction:

Ventricular dysfunction (450 drugs)

Browse all the conditions that are associated with Ventricular dysfunction:

Ventricular dysfunction (551 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mitoxantrone hydrochloride (the active ingredients of Mitoxantrone) and Mitoxantrone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.