Moduretic 5-50 and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Moduretic 5-50 (amiloride hydrochloride; hydrochlorothiazide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Omeprazole, and have Head injury.

The phase IV clinical study analyzes which people have Constipation when taking Moduretic 5-50. It is created by eHealthMe based on reports of 3,193 people who have side effects when taking Moduretic 5-50 from the FDA, and is updated regularly.

What is Moduretic 5-50?

Moduretic 5-50 has active ingredients of amiloride hydrochloride; hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 3,224 Moduretic 5-50 users. Check the latest studies of Moduretic 5-50.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,609 conditions by eHealthMe. Check the latest studies of Constipation.

On Jul, 09, 2026

3,193 people reported to have side effects when taking Moduretic 5-50.
Among them, 49 people (1.53%) have Constipation.

Could Moduretic 5-50 cause Constipation?

Among these 49 people:

How long have people been on Moduretic 5-50 when they have Constipation? *

What is the gender of people who have Constipation when taking Moduretic 5-50? *

female: 63.83 %
male: 36.17 %

What is the age of people who have Constipation when taking Moduretic 5-50? *

What are other drugs people take besides Moduretic 5-50? *

What are other side effects people have besides Constipation? *

Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 14 people, 28.57%
Weakness: 14 people, 28.57%
Nausea (feeling of having an urge to vomit): 10 people, 20.41%
Diarrhea: 10 people, 20.41%
Pneumonia: 10 people, 20.41%
Blood Bilirubin Increased: 8 people, 16.33%
Infection: 8 people, 16.33%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 8 people, 16.33%
Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 8 people, 16.33%
Anaemia (lack of blood): 8 people, 16.33%

What are the existing conditions these people have? *

Dyslipidaemia (abnormal amount of lipids): 8 people, 16.33%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 8 people, 16.33%
Head Injury: 8 people, 16.33%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 14.29%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 6 people, 12.24%
Pneumonia: 6 people, 12.24%
Anaemia (lack of blood): 5 people, 10.20%
Thrombocytopenia (decrease of platelets in blood): 4 people, 8.16%
Fever: 3 people, 6.12%
Parkinson's Disease: 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

Do you take Moduretic 5-50 and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Moduretic 5-50:

Moduretic 5-50 (3,224 reports)

Constipation treatments and more:

Constipation (337,879 reports)

How severe was Constipation and when was it recovered:

Constipation in Moduretic 5-50

Expand to all the drugs that have ingredients of amiloride hydrochloride; hydrochlorothiazide:

Constipation and drugs with ingredients of amiloride hydrochloride; hydrochlorothiazide

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Moduretic 5-50:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,004 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,609 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amiloride hydrochloride; hydrochlorothiazide (the active ingredients of Moduretic 5-50) and Moduretic 5-50 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.