Monoket and Hypertension aggravated - a phase IV clinical study of FDA data

Summary:

Hypertension aggravated is reported as a side effect among people who take Monoket (isosorbide mononitrate), especially for people who are male, 50-59 old, also take Lipitor, and have Stable angina.

The phase IV clinical study analyzes which people have Hypertension aggravated when taking Monoket. It is created by eHealthMe based on reports of 619 people who have side effects when taking Monoket from the FDA, and is updated regularly.

What is Monoket?

Monoket has active ingredients of isosorbide mononitrate. eHealthMe is studying from 623 Monoket users. Check the latest studies of Monoket.

What is Hypertension aggravated?

Hypertension aggravated (high blood pressure) is found to be associated with 2,749 drugs and 845 conditions by eHealthMe. Check the latest studies of Hypertension aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 03, 2026

619 people reported to have side effects when taking Monoket.
Among them, 23 people (3.72%) have Hypertension aggravated.

Could Monoket cause Hypertension aggravated?

Among these 23 people:

What is the gender of people who have Hypertension aggravated when taking Monoket? *

female: 18.18 %
male: 81.82 %

What is the age of people who have Hypertension aggravated when taking Monoket? *

What are other drugs people take besides Monoket? *

What are other side effects people have besides Hypertension aggravated? *

Chest Pain: 9 people, 39.13%
Iliac Artery Stenosis (the abnormal narrowing of a iliac artery): 8 people, 34.78%
Drug Tolerance Decreased: 7 people, 30.43%
Dyspnea (difficult or laboured breathing): 5 people, 21.74%
Weakness: 2 people, 8.70%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 8.70%
Cardiac Failure Congestive: 2 people, 8.70%
Diarrhea: 1 person, 4.35%
Dementia (madness): 1 person, 4.35%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 1 person, 4.35%

What are the existing conditions these people have? *

Stable Angina (a constant chest pain): 4 people, 17.39%
Heart Rate Increased: 1 person, 4.35%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 1 person, 4.35%
Cardiac Failure Chronic: 1 person, 4.35%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Monoket and have Hypertension aggravated?

- Check whether Hypertension aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Monoket:

Monoket (623 reports)

Browse all side effects of Monoket:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertension aggravated:

Hypertension aggravated (2,749 drugs)

Browse all the conditions that are associated with Hypertension aggravated:

Hypertension aggravated (845 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide mononitrate (the active ingredients of Monoket) and Monoket (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.