Motegrity and Nausea and vomiting - a phase IV clinical study of FDA data

Summary:

Nausea and vomiting is reported as a side effect among people who take Motegrity (prucalopride succinate), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Phenergan, and have Constipation.

The phase IV clinical study analyzes which people have Nausea and vomiting when taking Motegrity. It is created by eHealthMe based on reports of 1,359 people who have side effects when taking Motegrity from the FDA, and is updated regularly.

What is Motegrity?

Motegrity has active ingredients of prucalopride succinate. eHealthMe is studying from 1,380 Motegrity users. Check the latest studies of Motegrity.

What is Nausea and vomiting?

Nausea and vomiting is found to be associated with 3,712 drugs and 5,746 conditions by eHealthMe. Check the latest studies of Nausea and vomiting.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

1,359 people reported to have side effects when taking Motegrity.
Among them, 47 people (3.46%) have Nausea and vomiting.

Could Motegrity cause Nausea and vomiting?

Among these 47 people:

How long have people been on Motegrity when they have Nausea and vomiting? *

What is the gender of people who have Nausea and vomiting when taking Motegrity? *

female: 87.8 %
male: 12.2 %

What is the age of people who have Nausea and vomiting when taking Motegrity? *

What are other drugs people take besides Motegrity? *

What are other side effects people have besides Nausea and vomiting? *

Nausea (feeling of having an urge to vomit): 32 people, 68.09%
Headache (pain in head): 21 people, 44.68%
Diarrhea: 15 people, 31.91%
Abdominal Pain: 13 people, 27.66%
Dizziness: 12 people, 25.53%
Fatigue (feeling of tiredness): 11 people, 23.40%
Chest Pain: 8 people, 17.02%
Constipation: 8 people, 17.02%
Pain: 6 people, 12.77%
Abdominal Pain Upper: 6 people, 12.77%

What are the existing conditions these people have? *

Constipation: 14 people, 29.79%
Nausea (feeling of having an urge to vomit): 5 people, 10.64%
Immune System Disorder: 4 people, 8.51%
Asthma: 3 people, 6.38%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 6.38%
Hereditary Angioedema (recurrent episodes of severe swelling): 3 people, 6.38%
Organising Pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue): 3 people, 6.38%
Impaired Gastric Emptying: 3 people, 6.38%
Migraine (headache): 2 people, 4.26%
Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 2 people, 4.26%

* Approximation only. Some reports may have incomplete information.

Do you take Motegrity and have Nausea and vomiting?

- Check whether Nausea and vomiting is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Motegrity:

Motegrity (1,380 reports)

Browse all side effects of Motegrity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nausea and vomiting:

Nausea and vomiting (3,712 drugs)

Browse all the conditions that are associated with Nausea and vomiting:

Nausea and vomiting (5,746 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on prucalopride succinate (the active ingredients of Motegrity) and Motegrity (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.