Motrin and Impaired driving ability - a phase IV clinical study of FDA data

Summary:

Impaired driving ability is reported as a side effect among people who take Motrin (ibuprofen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Depression.

The phase IV clinical study analyzes which people have Impaired driving ability when taking Motrin. It is created by eHealthMe based on reports of 37,107 people who have side effects when taking Motrin from the FDA, and is updated regularly.

What is Motrin?

Motrin has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 38,332 Motrin users. Check the latest studies of Motrin.

What is Impaired driving ability?

Impaired driving ability is found to be associated with 740 drugs and 932 conditions by eHealthMe. Check the latest studies of Impaired driving ability.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

37,107 people reported to have side effects when taking Motrin.
Among them, 44 people (0.12%) have Impaired driving ability.

Could Motrin cause Impaired driving ability?

Among these 44 people:

How long have people been on Motrin when they have Impaired driving ability? *

What is the gender of people who have Impaired driving ability when taking Motrin? *

female: 86.36 %
male: 13.64 %

What is the age of people who have Impaired driving ability when taking Motrin? *

What are other drugs people take besides Motrin? *

What are other side effects people have besides Impaired driving ability? *

Nausea (feeling of having an urge to vomit): 12 people, 27.27%
Dizziness: 11 people, 25.00%
Insomnia (sleeplessness): 10 people, 22.73%
Vision Blurred: 9 people, 20.45%
High Blood Pressure: 9 people, 20.45%
Fall: 8 people, 18.18%
Memory Loss: 8 people, 18.18%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 7 people, 15.91%
Confusional State: 7 people, 15.91%
Activities Of Daily Living Impaired: 7 people, 15.91%

What are the existing conditions these people have? *

Depression: 5 people, 11.36%
Back Pain: 4 people, 9.09%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 6.82%
Quit Smoking: 3 people, 6.82%
High Blood Cholesterol: 3 people, 6.82%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 6.82%
Insomnia (sleeplessness): 3 people, 6.82%
Conjunctivitis Allergic (inflammation of the conjunctiva due to allergy): 3 people, 6.82%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 6.82%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

Do you take Motrin and have Impaired driving ability?

- Check whether Impaired driving ability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Motrin:

Motrin (38,332 reports)

Browse all side effects of Motrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Impaired driving ability:

Impaired driving ability (740 drugs)

Browse all the conditions that are associated with Impaired driving ability:

Impaired driving ability (932 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Motrin) and Motrin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.