Ms contin and Icterus - a phase IV clinical study of FDA data

Summary:

Icterus is reported as a side effect among people who take Ms contin (morphine sulfate), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Cisplatin, and have Cancer pain.

The phase IV clinical study analyzes which people have Icterus when taking Ms contin. It is created by eHealthMe based on reports of 68,873 people who have side effects when taking Ms contin from the FDA, and is updated regularly.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,288 Ms contin users. Check the latest studies of Ms contin.

What is Icterus?

Icterus (yellowish pigmentation of the skin) is found to be associated with 2,146 drugs and 2,988 conditions by eHealthMe. Check the latest studies of Icterus.



On Oct, 28, 2025

68,873 people reported to have side effects when taking Ms contin.
Among them, 43 people (0.06%) have Icterus.

Could Ms contin cause Icterus?

Among these 43 people:

How long have people been on Ms contin when they have Icterus? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Icterus when taking Ms contin? *

  • female: 46.51 %
  • male: 53.49 %

What is the age of people who have Icterus when taking Ms contin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 13.51 %
  • 40-49: 40.54 %
  • 50-59: 27.03 %
  • 60+: 18.92 %

What are other drugs people take besides Ms contin? *

  1. Cisplatin: 12 people, 27.91%
  2. Oxycontin: 9 people, 20.93%
  3. Morphine: 9 people, 20.93%
  4. Gemcitabine: 8 people, 18.60%
  5. Dilaudid: 7 people, 16.28%
  6. Fentanyl: 5 people, 11.63%
  7. Vicodin: 4 people, 9.30%
  8. Methylprednisolone: 4 people, 9.30%
  9. Maxolon: 4 people, 9.30%
  10. Iressa: 4 people, 9.30%

What are other side effects people have besides Icterus? *

  1. Anaemia (lack of blood): 14 people, 32.56%
  2. Hypotension (abnormally low blood pressure): 13 people, 30.23%
  3. Weight Decreased: 11 people, 25.58%
  4. Neoplasm Progression (growth of tumour): 10 people, 23.26%
  5. Nausea (feeling of having an urge to vomit): 9 people, 20.93%
  6. Urinary Retention (the inability to completely or partially empty the bladder): 8 people, 18.60%
  7. Therapeutic Response Decreased (less preventive response): 8 people, 18.60%
  8. Hepatic Enzyme Increased: 8 people, 18.60%
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 8 people, 18.60%
  10. Consciousness - Decreased: 8 people, 18.60%

What are the existing conditions these people have? *

  1. Cancer Pain: 12 people, 27.91%
  2. Lip And/or Oral Cavity Cancer Recurrent (recurrence of cancer of lip or mouth): 4 people, 9.30%
  3. Follicle Centre Lymphoma, Follicular Grade I, Ii, Iii Stage Iv: 3 people, 6.98%
  4. Headache (pain in head): 2 people, 4.65%
  5. Rectal Cancer (cancer of rectum): 2 people, 4.65%
  6. Depression: 2 people, 4.65%
  7. Lung Cancer - Non-Small Cell (lung cancer): 2 people, 4.65%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 4.65%
  9. Nausea (feeling of having an urge to vomit): 2 people, 4.65%
  10. Breakthrough Pain: 2 people, 4.65%

* Approximation only. Some reports may have incomplete information.

Do you take Ms contin and have Icterus?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ms contin:

Icterus treatments and more:

How severe was Icterus and when was it recovered:

Expand to all the drugs that have ingredients of morphine sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Icterus:

Browse all the conditions that are associated with Icterus:

Drugs similar to Ms contin and Icterus :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate (the active ingredients of Ms contin) and Ms contin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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