Ms contin and Tibia fracture - a phase IV clinical study of FDA data

Summary:

Tibia fracture is reported as a side effect among people who take Ms contin (morphine sulfate), especially for people who are male, 40-49 old, also take Dilaudid, and have Muscle spasms.

The phase IV clinical study analyzes which people have Tibia fracture when taking Ms contin. It is created by eHealthMe based on reports of 68,873 people who have side effects when taking Ms contin from the FDA, and is updated regularly.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.

What is Tibia fracture?

Tibia fracture (fracture of lower leg bone) is found to be associated with 644 drugs and 669 conditions by eHealthMe. Check the latest studies of Tibia fracture.



On Jul, 07, 2026

68,873 people reported to have side effects when taking Ms contin.
Among them, 24 people (0.03%) have Tibia fracture.

Could Ms contin cause Tibia fracture?

Among these 24 people:

What is the gender of people who have Tibia fracture when taking Ms contin? *

  • female: 17.39 %
  • male: 82.61 %

What is the age of people who have Tibia fracture when taking Ms contin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 5.56 %
  • 30-39: 5.56 %
  • 40-49: 38.89 %
  • 50-59: 22.22 %
  • 60+: 27.78 %

What are other drugs people take besides Ms contin? *

  1. Oxycontin: 8 people, 33.33%
  2. Dilaudid: 8 people, 33.33%
  3. Xanax: 7 people, 29.17%
  4. Neupogen: 6 people, 25.00%
  5. Percocet: 6 people, 25.00%
  6. Ryzolt: 6 people, 25.00%
  7. Butrans: 6 people, 25.00%
  8. Advair Diskus 100/50: 5 people, 20.83%
  9. Fosamax: 5 people, 20.83%
  10. Vitamin D3: 5 people, 20.83%

What are other side effects people have besides Tibia fracture? *

  1. Fibula Fracture: 11 people, 45.83%
  2. Drug Dependence: 7 people, 29.17%
  3. Fall: 6 people, 25.00%
  4. Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 6 people, 25.00%
  5. Overdose: 5 people, 20.83%
  6. Intervertebral Disc Degeneration (spinal disc degeneration): 5 people, 20.83%
  7. Rib Fracture: 5 people, 20.83%
  8. Joint Injury: 5 people, 20.83%
  9. Ankle Fracture: 4 people, 16.67%
  10. Muscle Spasms (muscle contraction): 4 people, 16.67%

What are the existing conditions these people have? *

  1. Muscle Spasms (muscle contraction): 7 people, 29.17%
  2. Sleep Disorder: 6 people, 25.00%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 16.67%
  4. Breakthrough Pain: 4 people, 16.67%
  5. Intervertebral Disc Degeneration (spinal disc degeneration): 4 people, 16.67%
  6. Limb Injury: 4 people, 16.67%
  7. Abdominal Distension: 3 people, 12.50%
  8. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 12.50%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.50%
  10. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Ms contin and have Tibia fracture?

- Check whether Tibia fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ms contin:

Tibia fracture treatments and more:

How severe was Tibia fracture and when was it recovered:

Expand to all the drugs that have ingredients of morphine sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tibia fracture:

Browse all the conditions that are associated with Tibia fracture:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate (the active ingredients of Ms contin) and Ms contin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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