Msm and Arthropathy - a phase IV clinical study of FDA data

Summary:

Arthropathy is reported as a side effect among people who take Msm (methylsulfonylmethane), especially for people who are female, 50-59 old, also take Rabeprazole, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Arthropathy when taking Msm. It is created by eHealthMe based on reports of 978 people who have side effects when taking Msm from the FDA, and is updated regularly.

What is Msm?

Msm has active ingredients of methylsulfonylmethane. It is often used in joint pain. eHealthMe is studying from 1,210 Msm users. Check the latest studies of Msm.

What is Arthropathy?

Arthropathy is found to be associated with 1,595 drugs and 1,686 conditions by eHealthMe. Check the latest studies of Arthropathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

978 people reported to have side effects when taking Msm.
Among them, 21 people (2.15%) have Arthropathy.

Among these 21 people:

What is the gender of people who have Arthropathy when taking Msm? *

female: 84.21 %
male: 15.79 %

What is the age of people who have Arthropathy when taking Msm? *

What are other drugs people take besides Msm? *

What are other side effects people have besides Arthropathy? *

Fall: 15 people, 71.43%
Joint Swelling: 14 people, 66.67%
High Blood Cholesterol: 14 people, 66.67%
Joint Instability (a condition in which the joints aren't sufficiently supported): 13 people, 61.90%
Synovitis (inflammation of the synovial membrane): 13 people, 61.90%
Musculoskeletal Disorder (disease of the body's muscles, joints, tendons, ligaments and nerves): 13 people, 61.90%
Open Fracture: 13 people, 61.90%
Diabetes: 13 people, 61.90%
Gait Disturbance: 10 people, 47.62%
Fatigue (feeling of tiredness): 9 people, 42.86%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 14 people, 66.67%
High Blood Cholesterol: 2 people, 9.52%
Urinary Tract Infection: 1 person, 4.76%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 4.76%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 1 person, 4.76%
Polyarthritis (arthritis which involves 5 or more joints simultaneously): 1 person, 4.76%
Myositis (inflammation of the muscles): 1 person, 4.76%
Metastases To Bone (cancer spreads to bone): 1 person, 4.76%
Lung Disorder (lung disease): 1 person, 4.76%
Computerised Tomogram Abnormal: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Msm and have Arthropathy?

- Check whether Arthropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Msm:

Msm (1,210 reports)

Arthropathy treatments and more:

Arthropathy (75,984 reports)

Browse all side effects of Msm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Arthropathy:

Arthropathy (1,595 drugs)

Browse all the conditions that are associated with Arthropathy:

Arthropathy (1,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylsulfonylmethane (the active ingredients of Msm) and Msm (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.