Msm and Itching - a phase IV clinical study of FDA data

Summary:

Itching is reported as a side effect among people who take Msm (methylsulfonylmethane), especially for people who are female, 60+ old, also take Vitamin D3, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Itching when taking Msm. It is created by eHealthMe based on reports of 978 people who have side effects when taking Msm from the FDA, and is updated regularly.

What is Msm?

Msm has active ingredients of methylsulfonylmethane. It is often used in joint pain. eHealthMe is studying from 1,210 Msm users. Check the latest studies of Msm.

What is Itching?

Itching is found to be associated with 3,211 drugs and 4,538 conditions by eHealthMe. Check the latest studies of Itching.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

978 people reported to have side effects when taking Msm.
Among them, 36 people (3.68%) have Itching.

Among these 36 people:

What is the gender of people who have Itching when taking Msm? *

female: 73.53 %
male: 26.47 %

What is the age of people who have Itching when taking Msm? *

What are other drugs people take besides Msm? *

What are other side effects people have besides Itching? *

Rashes (redness): 17 people, 47.22%
Pain: 13 people, 36.11%
Nausea (feeling of having an urge to vomit): 8 people, 22.22%
Abdominal Pain Upper: 8 people, 22.22%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 19.44%
Skin Burning Sensation: 7 people, 19.44%
Respiratory Rate Increased (excess breathing rate/min): 6 people, 16.67%
Feeling Cold: 6 people, 16.67%
Infusion Related Reaction: 6 people, 16.67%
Fatigue (feeling of tiredness): 6 people, 16.67%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 13.89%
High Blood Pressure: 4 people, 11.11%
Hair Loss: 3 people, 8.33%
Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 3 people, 8.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 5.56%
Pain: 2 people, 5.56%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 2 people, 5.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.56%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.56%
Asthma: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Msm and have Itching?

- Check whether Itching is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Msm:

Msm (1,210 reports)

Itching treatments and more:

Itching (398,823 reports)

Browse all side effects of Msm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Itching:

Itching (3,211 drugs)

Browse all the conditions that are associated with Itching:

Itching (4,538 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylsulfonylmethane (the active ingredients of Msm) and Msm (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.