Mucinex and Hypernatraemia - a phase IV clinical study of FDA data

Summary:

Hypernatraemia is reported as a side effect among people who take Mucinex (guaifenesin), especially for people who are male, 60+ old, also take Furosemide, and have Cardiac disorder.

The phase IV clinical study analyzes which people have Hypernatraemia when taking Mucinex. It is created by eHealthMe based on reports of 28,090 people who have side effects when taking Mucinex from the FDA, and is updated regularly.

What is Mucinex?

Mucinex has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 29,749 Mucinex users. Check the latest studies of Mucinex.

What is Hypernatraemia?

Hypernatraemia (an abnormally high plasma concentration of sodium ions) is found to be associated with 663 drugs and 805 conditions by eHealthMe. Check the latest studies of Hypernatraemia.



On Apr, 27, 2026

28,090 people reported to have side effects when taking Mucinex.
Among them, 13 people (0.05%) have Hypernatraemia.

Could Mucinex cause Hypernatraemia?

Among these 13 people:

What is the gender of people who have Hypernatraemia when taking Mucinex? *

  • female: 38.46 %
  • male: 61.54 %

What is the age of people who have Hypernatraemia when taking Mucinex? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 30 %
  • 60+: 70 %

What are other drugs people take besides Mucinex? *

  1. Acetaminophen: 6 people, 46.15%
  2. Furosemide: 6 people, 46.15%
  3. Levaquin: 5 people, 38.46%
  4. Spiriva: 5 people, 38.46%
  5. Albuterol: 4 people, 30.77%
  6. Potassium: 4 people, 30.77%
  7. Rocephin: 4 people, 30.77%
  8. Digoxin: 4 people, 30.77%
  9. Novolog: 4 people, 30.77%
  10. Naproxen: 4 people, 30.77%

What are other side effects people have besides Hypernatraemia? *

  1. Anaemia (lack of blood): 8 people, 61.54%
  2. Weight Increased: 7 people, 53.85%
  3. Oedema Peripheral (superficial swelling): 6 people, 46.15%
  4. Abdominal Distension: 5 people, 38.46%
  5. Enlarged Heart: 5 people, 38.46%
  6. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 5 people, 38.46%
  7. Dehydration (dryness resulting from the removal of water): 5 people, 38.46%
  8. High Blood Pressure: 5 people, 38.46%
  9. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 38.46%
  10. Fatigue (feeling of tiredness): 4 people, 30.77%

What are the existing conditions these people have? *

  1. Immunodeficiency: 3 people, 23.08%
  2. Cardiac Disorder: 3 people, 23.08%
  3. Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 2 people, 15.38%
  4. Prostatitis (inflammation of the prostate gland): 1 person, 7.69%
  5. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 1 person, 7.69%
  6. Immunodeficiency Common Variable: 1 person, 7.69%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.69%
  8. High Blood Pressure: 1 person, 7.69%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
  10. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Mucinex and have Hypernatraemia?

- Check whether Hypernatraemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mucinex:

Hypernatraemia treatments and more:

How severe was Hypernatraemia and when was it recovered:

Expand to all the drugs that have ingredients of guaifenesin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mucinex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypernatraemia:

Browse all the conditions that are associated with Hypernatraemia:


How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin (the active ingredients of Mucinex) and Mucinex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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