Myleran and Neurotoxicity - a phase IV clinical study of FDA data

Summary:

Neurotoxicity is reported as a side effect among people who take Myleran (busulfan), especially for people who are male, 2-9 old, also take Thiotepa, and have Ewing's sarcoma metastatic.

The phase IV clinical study analyzes which people have Neurotoxicity when taking Myleran. It is created by eHealthMe based on reports of 501 people who have side effects when taking Myleran from the FDA, and is updated regularly.

What is Myleran?

Myleran has active ingredients of busulfan. eHealthMe is studying from 504 Myleran users. Check the latest studies of Myleran.

What is Neurotoxicity?

Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system) is found to be associated with 697 drugs and 846 conditions by eHealthMe. Check the latest studies of Neurotoxicity.

On Jan, 31, 2026

501 people reported to have side effects when taking Myleran.
Among them, 14 people (2.79%) have Neurotoxicity.

Among these 14 people:

What is the gender of people who have Neurotoxicity when taking Myleran? *

female: 35.71 %
male: 64.29 %

What is the age of people who have Neurotoxicity when taking Myleran? *

What are other drugs people take besides Myleran? *

What are other side effects people have besides Neurotoxicity? *

Thrombocytopenia (decrease of platelets in blood): 5 people, 35.71%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 5 people, 35.71%
Partial Seizures (seizures which affect only a part of the brain at onset): 3 people, 21.43%
Lung Infection: 3 people, 21.43%
Gastrointestinal Toxicity (damage to digestive tract by any substance): 2 people, 14.29%
Febrile Neutropenia (fever with reduced white blood cells): 2 people, 14.29%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 14.29%
Radiation Skin Sensitivity: 1 person, 7.14%
Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 7.14%
Necrosis (the death of body tissue): 1 person, 7.14%

What are the existing conditions these people have? *

Partial Seizures (seizures which affect only a part of the brain at onset): 1 person, 7.14%
Ewing's Sarcoma Metastatic (malignant small, round, blue cell tumour-metastatic): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Myleran and have Neurotoxicity?

- Check whether Neurotoxicity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Myleran:

Myleran (504 reports)

Neurotoxicity treatments and more:

Neurotoxicity (16,742 reports)

Browse all side effects of Myleran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neurotoxicity:

Neurotoxicity (697 drugs)

Browse all the conditions that are associated with Neurotoxicity:

Neurotoxicity (846 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on busulfan (the active ingredients of Myleran) and Myleran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.