Mysoline and Coma - a phase IV clinical study of FDA data

Summary:

Coma is reported as a side effect among people who take Mysoline (primidone), especially for people who are male, 60+ old, have been taking the drug for 10+ years also take Tegretol, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Coma when taking Mysoline. It is created by eHealthMe based on reports of 2,781 people who have side effects when taking Mysoline from the FDA, and is updated regularly.

What is Mysoline?

Mysoline has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 2,849 Mysoline users. Check the latest studies of Mysoline.

What is Coma?

Coma (state of unconsciousness lasting more than six hours) is found to be associated with 2,794 drugs and 3,207 conditions by eHealthMe. Check the latest studies of Coma.

On Jun, 22, 2026

2,781 people reported to have side effects when taking Mysoline.
Among them, 47 people (1.69%) have Coma.

Among these 47 people:

How long have people been on Mysoline when they have Coma? *

What is the gender of people who have Coma when taking Mysoline? *

female: 43.48 %
male: 56.52 %

What is the age of people who have Coma when taking Mysoline? *

What are other drugs people take besides Mysoline? *

What are other side effects people have besides Coma? *

Itching: 10 people, 21.28%
Dizziness: 10 people, 21.28%
Weakness: 9 people, 19.15%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 9 people, 19.15%
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 8 people, 17.02%
Insomnia (sleeplessness): 8 people, 17.02%
Brain Damage: 8 people, 17.02%
Hypermetropia (abnormal condition in which vision for distant objects is better than for near objects): 8 people, 17.02%
Nearsightedness (difficulty in seeing the far objects): 8 people, 17.02%
Headache (pain in head): 8 people, 17.02%

What are the existing conditions these people have? *

Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 6.38%
Bipolar Disorder (mood disorder): 3 people, 6.38%
Stress And Anxiety: 3 people, 6.38%
High Blood Cholesterol: 3 people, 6.38%
Depression: 3 people, 6.38%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.38%
Muscle Spasms (muscle contraction): 2 people, 4.26%
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 2 people, 4.26%
Heart Disease: 2 people, 4.26%
Neuralgia (pain in one or more nerves): 2 people, 4.26%

* Approximation only. Some reports may have incomplete information.

Do you take Mysoline and have Coma?

- Check whether Coma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mysoline:

Mysoline (2,849 reports)

Coma treatments and more:

Coma (57,420 reports)

Browse all side effects of Mysoline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Coma:

Coma (2,794 drugs)

Browse all the conditions that are associated with Coma:

Coma (3,207 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on primidone (the active ingredients of Mysoline) and Mysoline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.