Mysoline and Irritable bowel syndrome - a phase IV clinical study of FDA data

Summary:

Irritable bowel syndrome is reported as a side effect among people who take Mysoline (primidone), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Dilantin, and have Osteoporosis.

The phase IV clinical study analyzes which people have Irritable bowel syndrome when taking Mysoline. It is created by eHealthMe based on reports of 2,781 people who have side effects when taking Mysoline from the FDA, and is updated regularly.

What is Mysoline?

Mysoline has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 2,849 Mysoline users. Check the latest studies of Mysoline.

What is Irritable bowel syndrome?

Irritable bowel syndrome is found to be associated with 1,316 drugs and 2,128 conditions by eHealthMe. Check the latest studies of Irritable bowel syndrome.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

2,781 people reported to have side effects when taking Mysoline.
Among them, 13 people (0.47%) have Irritable bowel syndrome.

Could Mysoline cause Irritable bowel syndrome?

Among these 13 people:

How long have people been on Mysoline when they have Irritable bowel syndrome? *

What is the gender of people who have Irritable bowel syndrome when taking Mysoline? *

female: 92.31 %
male: 7.69 %

What is the age of people who have Irritable bowel syndrome when taking Mysoline? *

What are other drugs people take besides Mysoline? *

What are other side effects people have besides Irritable bowel syndrome? *

Weakness: 7 people, 53.85%
Chest Pain: 6 people, 46.15%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 6 people, 46.15%
Urinary Tract Infection: 6 people, 46.15%
Low Turnover Osteopathy (slow removal of old bone and its replacement by new bone): 5 people, 38.46%
Gastroenteritis (inflammation of stomach and intestine): 5 people, 38.46%
Head Injury: 5 people, 38.46%
Pain In Extremity: 5 people, 38.46%
Osteoporosis (bones weak and more likely to break): 5 people, 38.46%
Oedema Peripheral (superficial swelling): 5 people, 38.46%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 5 people, 38.46%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 15.38%
Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 7.69%
Stress And Anxiety: 1 person, 7.69%
Stable Angina (a constant chest pain): 1 person, 7.69%
Sleep Disorder: 1 person, 7.69%
Otitis (ear infection): 1 person, 7.69%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 7.69%
High Blood Cholesterol: 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Mysoline and have Irritable bowel syndrome?

- Check whether Irritable bowel syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mysoline:

Mysoline (2,849 reports)

Browse all side effects of Mysoline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Irritable bowel syndrome:

Irritable bowel syndrome (1,316 drugs)

Browse all the conditions that are associated with Irritable bowel syndrome:

Irritable bowel syndrome (2,128 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on primidone (the active ingredients of Mysoline) and Mysoline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.