Mysoline and Renal failure aggravated - a phase IV clinical study of FDA data

Summary:

Renal failure aggravated is reported as a side effect among people who take Mysoline (primidone), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Synthroid, and have High blood pressure.

The phase IV clinical study analyzes which people have Renal failure aggravated when taking Mysoline. It is created by eHealthMe based on reports of 2,781 people who have side effects when taking Mysoline from the FDA, and is updated regularly.

What is Mysoline?

Mysoline has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 2,849 Mysoline users. Check the latest studies of Mysoline.

What is Renal failure aggravated?

Renal failure aggravated is found to be associated with 2,378 drugs and 795 conditions by eHealthMe. Check the latest studies of Renal failure aggravated.



On Aug, 07, 2026

2,781 people reported to have side effects when taking Mysoline.
Among them, 71 people (2.55%) have Renal failure aggravated.

Could Mysoline cause Renal failure aggravated?

Among these 71 people:

How long have people been on Mysoline when they have Renal failure aggravated? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 33.33 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 66.67 %
  • 10+ years: 0.0 %

What is the gender of people who have Renal failure aggravated when taking Mysoline? *

  • female: 41.18 %
  • male: 58.82 %

What is the age of people who have Renal failure aggravated when taking Mysoline? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 9.23 %
  • 40-49: 16.92 %
  • 50-59: 7.69 %
  • 60+: 66.15 %

What are other drugs people take besides Mysoline? *

  1. Plavix: 12 people, 16.90%
  2. Synthroid: 12 people, 16.90%
  3. Lyrica: 11 people, 15.49%
  4. Nexium: 10 people, 14.08%
  5. Effexor: 10 people, 14.08%
  6. Aspirin: 9 people, 12.68%
  7. Prilosec: 9 people, 12.68%
  8. Neurontin: 9 people, 12.68%
  9. Baclofen: 9 people, 12.68%
  10. Lipitor: 8 people, 11.27%

What are other side effects people have besides Renal failure aggravated? *

  1. Dyspnea (difficult or laboured breathing): 11 people, 15.49%
  2. Chronic Kidney Disease: 10 people, 14.08%
  3. Cytolytic Hepatitis (dissolution or destruction of a liver cell): 10 people, 14.08%
  4. Cardiac Failure Congestive: 8 people, 11.27%
  5. Renal Injury (kidney injury): 8 people, 11.27%
  6. Stress And Anxiety: 8 people, 11.27%
  7. Multi-Organ Failure (multisystem organ failure): 7 people, 9.86%
  8. Injury: 7 people, 9.86%
  9. Emotional Distress: 7 people, 9.86%
  10. Hepatic Necrosis (large portions of liver die off due to severe liver disease): 6 people, 8.45%

What are the existing conditions these people have? *

  1. High Blood Pressure: 12 people, 16.90%
  2. Hiv Infection: 11 people, 15.49%
  3. High Blood Cholesterol: 9 people, 12.68%
  4. Diabetes: 8 people, 11.27%
  5. Neuralgia (pain in one or more nerves): 7 people, 9.86%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 9.86%
  7. Enlarged Prostate: 6 people, 8.45%
  8. Gastritis (inflammation of stomach): 6 people, 8.45%
  9. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 5 people, 7.04%
  10. Hepatitis B: 5 people, 7.04%

* Approximation only. Some reports may have incomplete information.

Do you take Mysoline and have Renal failure aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mysoline:

Renal failure aggravated treatments and more:

How severe was Renal failure aggravated and when was it recovered:

Expand to all the drugs that have ingredients of primidone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mysoline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Renal failure aggravated:

Browse all the conditions that are associated with Renal failure aggravated:


How the study uses the data?

The study uses data from the FDA. It is based on primidone (the active ingredients of Mysoline) and Mysoline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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