Nabumetone and Aphonia - a phase IV clinical study of FDA data

Summary:

Aphonia is reported as a side effect among people who take Nabumetone (nabumetone), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Effexor, and have Hereditary angioedema.

The phase IV clinical study analyzes which people have Aphonia when taking Nabumetone. It is created by eHealthMe based on reports of 9,121 people who have side effects when taking Nabumetone from the FDA, and is updated regularly.

What is Nabumetone?

Nabumetone has active ingredients of nabumetone. It is often used in arthritis. eHealthMe is studying from 9,554 Nabumetone users. Check the latest studies of Nabumetone.

What is Aphonia?

Aphonia (inability to produce voice) is found to be associated with 883 drugs and 848 conditions by eHealthMe. Check the latest studies of Aphonia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

9,121 people reported to have side effects when taking Nabumetone.
Among them, 16 people (0.18%) have Aphonia.

Among these 16 people:

How long have people been on Nabumetone when they have Aphonia? *

What is the gender of people who have Aphonia when taking Nabumetone? *

female: 86.67 %
male: 13.33 %

What is the age of people who have Aphonia when taking Nabumetone? *

What are other drugs people take besides Nabumetone? *

What are other side effects people have besides Aphonia? *

Dizziness: 8 people, 50.00%
Stress And Anxiety: 6 people, 37.50%
Hoarseness Or Changing Voice: 6 people, 37.50%
Fall: 6 people, 37.50%
Sensation Of Foreign Body: 5 people, 31.25%
Burning Sensation: 5 people, 31.25%
Chest Pain: 5 people, 31.25%
Laryngitis (inflammation of the larynx): 5 people, 31.25%
Injury: 4 people, 25.00%
Nasopharyngitis (inflammation of the nasopharynx): 4 people, 25.00%

What are the existing conditions these people have? *

Hereditary Angioedema (recurrent episodes of severe swelling): 5 people, 31.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 25.00%
Nausea (feeling of having an urge to vomit): 3 people, 18.75%
Connective Tissue Disorder (any disease that has the connective tissues of the body): 3 people, 18.75%
High Blood Cholesterol: 3 people, 18.75%
High Blood Pressure: 2 people, 12.50%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 12.50%
Pain In Extremity: 2 people, 12.50%
Dyspnea (difficult or laboured breathing): 2 people, 12.50%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Nabumetone and have Aphonia?

- Check whether Aphonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nabumetone:

Nabumetone (9,554 reports)

Aphonia treatments and more:

Aphonia (15,979 reports)

Browse all side effects of Nabumetone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aphonia:

Aphonia (883 drugs)

Browse all the conditions that are associated with Aphonia:

Aphonia (848 conditions)

Related publications that referenced our studies

Hung SC, Liao KF, Hung HC, Lin CL, Lai SW, Lin CH, "Nabumetone use and risk of acute pancreatitis in a case-control study", Pancreatology, 2016 Jun .
Hung SC, Liao KF, Hung HC, Lin CL, Lai SW, Lin CH, "Nabumetone use and risk of acute pancreatitis in a case-control study", Pancreatology, 2016 Jun .

How the study uses the data?

The study uses data from the FDA. It is based on nabumetone (the active ingredients of Nabumetone) and Nabumetone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.