Naloxone and Diverticulitis aggravated - a phase IV clinical study of FDA data

Summary:

Diverticulitis aggravated is reported as a side effect among people who take Naloxone (naloxone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Pantoprazole, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Diverticulitis aggravated when taking Naloxone. It is created by eHealthMe based on reports of 6,366 people who have side effects when taking Naloxone from the FDA, and is updated regularly.

What is Naloxone?

Naloxone has active ingredients of naloxone hydrochloride. eHealthMe is studying from 6,425 Naloxone users. Check the latest studies of Naloxone.

What is Diverticulitis aggravated?

Diverticulitis aggravated (digestive disease which involves the formation of pouches (diverticula) within the bowel wall) is found to be associated with 1,207 drugs and 441 conditions by eHealthMe. Check the latest studies of Diverticulitis aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

6,366 people reported to have side effects when taking Naloxone.
Among them, 22 people (0.35%) have Diverticulitis aggravated.

Could Naloxone cause Diverticulitis aggravated?

Among these 22 people:

How long have people been on Naloxone when they have Diverticulitis aggravated? *

What is the gender of people who have Diverticulitis aggravated when taking Naloxone? *

female: 42.86 %
male: 57.14 %

What is the age of people who have Diverticulitis aggravated when taking Naloxone? *

What are other drugs people take besides Naloxone? *

What are other side effects people have besides Diverticulitis aggravated? *

Metastases To Central Nervous System (cancer spreads to central nervous system): 9 people, 40.91%
Fever: 8 people, 36.36%
Nausea (feeling of having an urge to vomit): 7 people, 31.82%
Productive Cough: 7 people, 31.82%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 5 people, 22.73%
Joint Pain: 5 people, 22.73%
Kidney Infection (Pyelonephritis): 5 people, 22.73%
Large Intestine Perforation (hole in large intestine): 5 people, 22.73%
Oedema Peripheral (superficial swelling): 5 people, 22.73%
Dyspnea Exertional: 5 people, 22.73%

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 5 people, 22.73%
Nausea (feeling of having an urge to vomit): 4 people, 18.18%
Nausea And Vomiting: 4 people, 18.18%
Essential Hypertension (primary hypertension): 3 people, 13.64%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.64%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 3 people, 13.64%
Hepatocellular Carcinoma (liver cancer): 3 people, 13.64%
High Blood Pressure: 3 people, 13.64%
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 3 people, 13.64%
Constipation: 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

Do you take Naloxone and have Diverticulitis aggravated?

- Check whether Diverticulitis aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naloxone:

Naloxone (6,425 reports)

Browse all side effects of Naloxone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diverticulitis aggravated:

Diverticulitis aggravated (1,207 drugs)

Browse all the conditions that are associated with Diverticulitis aggravated:

Diverticulitis aggravated (441 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naloxone hydrochloride (the active ingredients of Naloxone) and Naloxone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.