Naloxone and Heart attack - a phase IV clinical study of FDA data

Summary:

Heart attack is reported as a side effect among people who take Naloxone (naloxone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Dexamethasone, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Heart attack when taking Naloxone. It is created by eHealthMe based on reports of 6,366 people who have side effects when taking Naloxone from the FDA, and is updated regularly.

What is Naloxone?

Naloxone has active ingredients of naloxone hydrochloride. eHealthMe is studying from 6,425 Naloxone users. Check the latest studies of Naloxone.

What is Heart attack?

Heart attack is found to be associated with 2,482 drugs and 3,296 conditions by eHealthMe. Check the latest studies of Heart attack.

On Jul, 06, 2026

6,366 people reported to have side effects when taking Naloxone.
Among them, 41 people (0.64%) have Heart attack.

Among these 41 people:

How long have people been on Naloxone when they have Heart attack? *

What is the gender of people who have Heart attack when taking Naloxone? *

female: 46.15 %
male: 53.85 %

What is the age of people who have Heart attack when taking Naloxone? *

What are other drugs people take besides Naloxone? *

What are other side effects people have besides Heart attack? *

Chest Pain: 11 people, 26.83%
High Blood Pressure: 10 people, 24.39%
Hyperlipidaemia (presence of excess lipids in the blood): 8 people, 19.51%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 19.51%
Fatigue (feeling of tiredness): 8 people, 19.51%
Memory Loss: 8 people, 19.51%
Multiple Myeloma (cancer of the plasma cells): 8 people, 19.51%
Sinusitis (inflammation of sinus): 7 people, 17.07%
Anaemia (lack of blood): 7 people, 17.07%
Bone Pain: 7 people, 17.07%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 9 people, 21.95%
Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 8 people, 19.51%
Atherosclerosis (disorder of the arteries): 8 people, 19.51%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 6 people, 14.63%
Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 2 people, 4.88%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 2 people, 4.88%
Pain: 2 people, 4.88%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 2 people, 4.88%
High Blood Pressure: 2 people, 4.88%
Depression: 2 people, 4.88%

* Approximation only. Some reports may have incomplete information.

Do you take Naloxone and have Heart attack?

- Check whether Heart attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naloxone:

Naloxone (6,425 reports)

Heart attack treatments and more:

Heart attack (266,145 reports)

Browse all side effects of Naloxone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart attack:

Heart attack (2,482 drugs)

Browse all the conditions that are associated with Heart attack:

Heart attack (3,296 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naloxone hydrochloride (the active ingredients of Naloxone) and Naloxone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.