Naloxone and Status epilepticus - a phase IV clinical study of FDA data

Summary:

Status epilepticus is reported as a side effect among people who take Naloxone (naloxone hydrochloride), especially for people who are male, 20-29 old, also take Escitalopram, and have Pneumonia staphylococcal.

The phase IV clinical study analyzes which people have Status epilepticus when taking Naloxone. It is created by eHealthMe based on reports of 6,366 people who have side effects when taking Naloxone from the FDA, and is updated regularly.

What is Naloxone?

Naloxone has active ingredients of naloxone hydrochloride. eHealthMe is studying from 6,425 Naloxone users. Check the latest studies of Naloxone.

What is Status epilepticus?

Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure) is found to be associated with 663 drugs and 949 conditions by eHealthMe. Check the latest studies of Status epilepticus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

6,366 people reported to have side effects when taking Naloxone.
Among them, 35 people (0.55%) have Status epilepticus.

Could Naloxone cause Status epilepticus?

Among these 35 people:

What is the gender of people who have Status epilepticus when taking Naloxone? *

female: 40.62 %
male: 59.38 %

What is the age of people who have Status epilepticus when taking Naloxone? *

What are other drugs people take besides Naloxone? *

What are other side effects people have besides Status epilepticus? *

Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 24 people, 68.57%
Body Temperature Increased: 20 people, 57.14%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 6 people, 17.14%
Cardiogenic Shock (inadequate circulation of blood): 5 people, 14.29%
Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 5 people, 14.29%
Drowsiness: 5 people, 14.29%
Cardiac Arrest: 5 people, 14.29%
Acute Hepatic Failure: 5 people, 14.29%
Cardiac Failure: 4 people, 11.43%
Overdose: 4 people, 11.43%

What are the existing conditions these people have? *

Pneumonia Staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus): 20 people, 57.14%
Depression: 4 people, 11.43%
Suicidal Ideation: 2 people, 5.71%
Visual Impairment: 1 person, 2.86%
Fever: 1 person, 2.86%
Acinetobacter Infection (infection by group of bacteria commonly found in soil and water): 1 person, 2.86%
Back Pain: 1 person, 2.86%
Corneal Epithelium Defect (outer layer defect of cornea): 1 person, 2.86%
Depressed Mood: 1 person, 2.86%
Depression Suicidal (suicide depressive disorder): 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Naloxone and have Status epilepticus?

- Check whether Status epilepticus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naloxone:

Naloxone (6,425 reports)

Browse all side effects of Naloxone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Status epilepticus:

Status epilepticus (663 drugs)

Browse all the conditions that are associated with Status epilepticus:

Status epilepticus (949 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naloxone hydrochloride (the active ingredients of Naloxone) and Naloxone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.