Naltrexone hydrochloride and Fever - a phase IV clinical study of FDA data

Summary:

Fever is reported as a side effect among people who take Naltrexone hydrochloride (naltrexone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Epinephrine, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Fever when taking Naltrexone hydrochloride. It is created by eHealthMe based on reports of 1,502 people who have side effects when taking Naltrexone hydrochloride from the FDA, and is updated regularly.

What is Naltrexone hydrochloride?

Naltrexone hydrochloride has active ingredients of naltrexone hydrochloride. It is often used in alcoholism. eHealthMe is studying from 1,712 Naltrexone hydrochloride users. Check the latest studies of Naltrexone hydrochloride.

What is Fever?

Fever is found to be associated with 3,494 drugs and 6,199 conditions by eHealthMe. Check the latest studies of Fever.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

1,502 people reported to have side effects when taking Naltrexone hydrochloride.
Among them, 75 people (4.99%) have Fever.

Could Naltrexone hydrochloride cause Fever?

Among these 75 people:

How long have people been on Naltrexone hydrochloride when they have Fever? *

What is the gender of people who have Fever when taking Naltrexone hydrochloride? *

female: 60.27 %
male: 39.73 %

What is the age of people who have Fever when taking Naltrexone hydrochloride? *

What are other drugs people take besides Naltrexone hydrochloride? *

Epinephrine: 28 people, 37.33%
Acetaminophen: 27 people, 36.00%
Magnesium: 19 people, 25.33%
Vitamin D3: 17 people, 22.67%
Fluticasone Propionate: 13 people, 17.33%
Sodium Chloride: 13 people, 17.33%
Zofran: 12 people, 16.00%
Lisinopril: 12 people, 16.00%
Humira: 12 people, 16.00%
Diazepam: 12 people, 16.00%

What are other side effects people have besides Fever? *

Pain: 42 people, 56.00%
Sinusitis (inflammation of sinus): 29 people, 38.67%
Headache (pain in head): 26 people, 34.67%
Joint Pain: 21 people, 28.00%
Fatigue (feeling of tiredness): 19 people, 25.33%
Diarrhea: 19 people, 25.33%
Nasopharyngitis (inflammation of the nasopharynx): 19 people, 25.33%
Malaise (a feeling of general discomfort or uneasiness): 16 people, 21.33%
High Blood Pressure: 16 people, 21.33%
Pneumonia: 16 people, 21.33%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 14 people, 18.67%
Multiple Myeloma (cancer of the plasma cells): 9 people, 12.00%
Immune System Disorder: 9 people, 12.00%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 9 people, 12.00%
Immunodeficiency: 6 people, 8.00%
Adverse Event: 6 people, 8.00%
Impaired Healing: 6 people, 8.00%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 4 people, 5.33%
Secondary Immunodeficiency (lack of immunity due to some disease): 3 people, 4.00%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 3 people, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Naltrexone hydrochloride and have Fever?

- Check whether Fever is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naltrexone hydrochloride:

Naltrexone hydrochloride (1,712 reports)

Fever treatments and more:

Fever (498,666 reports)

Browse all side effects of Naltrexone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fever:

Fever (3,494 drugs)

Browse all the conditions that are associated with Fever:

Fever (6,199 conditions)

Related publications that referenced our studies

Schiller D, Maieron A, Sch?fl R, Donnerer J, "Drug fever due to a single dose of pantoprazole", Pharmacology, 2015 Jan .
Behnoush B, Memarian A, Teimoory M, "Naltrexone Induced Serotonin Syndrome", International Journal of Medical Toxicology and Forensic Medicine, 2013 Apr .
Schiller D, Maieron A, Sch?fl R, Donnerer J, "Drug fever due to a single dose of pantoprazole", Pharmacology, 2015 Jan .
Behnoush B, Memarian A, Teimoory M, "Naltrexone Induced Serotonin Syndrome", International Journal of Medical Toxicology and Forensic Medicine, 2013 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on naltrexone hydrochloride (the active ingredients of Naltrexone hydrochloride) and Naltrexone hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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