Naltrexone hydrochloride and Insomnia - a phase IV clinical study of FDA data

Summary:

Insomnia is reported as a side effect among people who take Naltrexone hydrochloride (naltrexone hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Cimetidine, and have Complex regional pain syndrome.

The phase IV clinical study analyzes which people have Insomnia when taking Naltrexone hydrochloride. It is created by eHealthMe based on reports of 1,502 people who have side effects when taking Naltrexone hydrochloride from the FDA, and is updated regularly.

What is Naltrexone hydrochloride?

Naltrexone hydrochloride has active ingredients of naltrexone hydrochloride. It is often used in alcoholism. eHealthMe is studying from 1,712 Naltrexone hydrochloride users. Check the latest studies of Naltrexone hydrochloride.

What is Insomnia?

Insomnia (sleeplessness) is found to be associated with 3,119 drugs and 5,170 conditions by eHealthMe. Check the latest studies of Insomnia.

On Jul, 12, 2026

1,502 people reported to have side effects when taking Naltrexone hydrochloride.
Among them, 156 people (10.39%) have Insomnia.

Could Naltrexone hydrochloride cause Insomnia?

Among these 156 people:

How long have people been on Naltrexone hydrochloride when they have Insomnia? *

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What is the gender of people who have Insomnia when taking Naltrexone hydrochloride? *

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What is the age of people who have Insomnia when taking Naltrexone hydrochloride? *

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* Approximation only. Some reports may have incomplete information.

Do you take Naltrexone hydrochloride and have Insomnia?

- Check whether Insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naltrexone hydrochloride:

Naltrexone hydrochloride (1,712 reports)

Insomnia treatments and more:

Insomnia (438,078 reports)

How severe was Insomnia and when was it recovered:

Insomnia in Naltrexone hydrochloride

Expand to all the drugs that have ingredients of naltrexone hydrochloride:

Insomnia and drugs with ingredients of naltrexone hydrochloride (239 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naltrexone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia:

Insomnia (3,119 drugs)

Browse all the conditions that are associated with Insomnia:

Insomnia (5,170 conditions)

Related publications that referenced our studies

Behnoush B, Memarian A, Teimoory M, "Naltrexone Induced Serotonin Syndrome", International Journal of Medical Toxicology and Forensic Medicine, 2013 Apr .
Behnoush B, Memarian A, Teimoory M, "Naltrexone Induced Serotonin Syndrome", International Journal of Medical Toxicology and Forensic Medicine, 2013 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on naltrexone hydrochloride (the active ingredients of Naltrexone hydrochloride) and Naltrexone hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.