Naltrexone and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Naltrexone (naltrexone), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Vitamin C, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Constipation when taking Naltrexone. It is created by eHealthMe based on reports of 4,805 people who have side effects when taking Naltrexone from the FDA, and is updated regularly.

What is Naltrexone?

Naltrexone has active ingredients of naltrexone. eHealthMe is studying from 4,833 Naltrexone users. Check the latest studies of Naltrexone.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,614 conditions by eHealthMe. Check the latest studies of Constipation.

On May, 09, 2026

4,805 people reported to have side effects when taking Naltrexone.
Among them, 96 people (2.0%) have Constipation.

Among these 96 people:

How long have people been on Naltrexone when they have Constipation? *

What is the gender of people who have Constipation when taking Naltrexone? *

female: 73.17 %
male: 26.83 %

What is the age of people who have Constipation when taking Naltrexone? *

What are other drugs people take besides Naltrexone? *

What are other side effects people have besides Constipation? *

Nausea (feeling of having an urge to vomit): 32 people, 33.33%
Fatigue (feeling of tiredness): 26 people, 27.08%
Stress And Anxiety: 25 people, 26.04%
Malaise (a feeling of general discomfort or uneasiness): 24 people, 25.00%
Weight Decreased: 23 people, 23.96%
Tremor (trembling or shaking movements in one or more parts of your body): 22 people, 22.92%
Headache (pain in head): 20 people, 20.83%
Dizziness: 18 people, 18.75%
Memory Loss: 17 people, 17.71%
Pain: 17 people, 17.71%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 14 people, 14.58%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 11.46%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 9.38%
Alcoholism (problems with alcohol): 7 people, 7.29%
Migraine (headache): 7 people, 7.29%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 7.29%
Drug Dependence: 6 people, 6.25%
Stress And Anxiety: 6 people, 6.25%
Insomnia (sleeplessness): 6 people, 6.25%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Naltrexone and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naltrexone:

Naltrexone (4,833 reports)

Constipation treatments and more:

Constipation (337,879 reports)

Browse all side effects of Naltrexone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,004 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,614 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naltrexone (the active ingredients of Naltrexone) and Naltrexone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.