Naprosyn and Hypertensive crisis - a phase IV clinical study of FDA data

Summary:

Hypertensive crisis is reported as a side effect among people who take Naprosyn (naproxen), especially for people who are female, 60+ old, also take Lunesta, and have Delusion.

The phase IV clinical study analyzes which people have Hypertensive crisis when taking Naprosyn. It is created by eHealthMe based on reports of 16,337 people who have side effects when taking Naprosyn from the FDA, and is updated regularly.

What is Naprosyn?

Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.

What is Hypertensive crisis?

Hypertensive crisis is found to be associated with 783 drugs and 932 conditions by eHealthMe. Check the latest studies of Hypertensive crisis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

16,337 people reported to have side effects when taking Naprosyn.
Among them, 12 people (0.07%) have Hypertensive crisis.

Could Naprosyn cause Hypertensive crisis?

Among these 12 people:

What is the gender of people who have Hypertensive crisis when taking Naprosyn? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Hypertensive crisis when taking Naprosyn? *

What are other drugs people take besides Naprosyn? *

What are other side effects people have besides Hypertensive crisis? *

Feeling Abnormal: 5 people, 41.67%
Infection: 5 people, 41.67%
Catatonia (unresponsive to external stimuli): 4 people, 33.33%
Headache (pain in head): 4 people, 33.33%
Heart Attack: 4 people, 33.33%
High Blood Pressure: 4 people, 33.33%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 33.33%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 3 people, 25.00%
Meningitis Viral (viral inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 3 people, 25.00%
Chest Pain: 3 people, 25.00%

What are the existing conditions these people have? *

High Blood Pressure: 2 people, 16.67%
Delusion (a false belief or opinion): 2 people, 16.67%
Sleep Disorder: 1 person, 8.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 8.33%
Osteoporosis (bones weak and more likely to break): 1 person, 8.33%
Nervousness: 1 person, 8.33%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 1 person, 8.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
Metastases To Bone (cancer spreads to bone): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Naprosyn and have Hypertensive crisis?

- Check whether Hypertensive crisis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naprosyn:

Naprosyn (16,738 reports)

Browse all side effects of Naprosyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertensive crisis:

Hypertensive crisis (783 drugs)

Browse all the conditions that are associated with Hypertensive crisis:

Hypertensive crisis (932 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naproxen (the active ingredients of Naprosyn) and Naprosyn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.