Naprosyn and Hypertonic bladder - a phase IV clinical study of FDA data

Summary:

Hypertonic bladder is reported as a side effect among people who take Naprosyn (naproxen), especially for people who are female, 50-59 old, also take Lyrica, and have Breast cancer.

The phase IV clinical study analyzes which people have Hypertonic bladder when taking Naprosyn. It is created by eHealthMe based on reports of 16,337 people who have side effects when taking Naprosyn from the FDA, and is updated regularly.

What is Naprosyn?

Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.

What is Hypertonic bladder?

Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate) is found to be associated with 617 drugs and 508 conditions by eHealthMe. Check the latest studies of Hypertonic bladder.

On Dec, 19, 2025

16,337 people reported to have side effects when taking Naprosyn.
Among them, 28 people (0.17%) have Hypertonic bladder.

Could Naprosyn cause Hypertonic bladder?

Among these 28 people:

What is the gender of people who have Hypertonic bladder when taking Naprosyn? *

female: 96.3 %
male: 3.7 %

What is the age of people who have Hypertonic bladder when taking Naprosyn? *

What are other drugs people take besides Naprosyn? *

What are other side effects people have besides Hypertonic bladder? *

Nausea (feeling of having an urge to vomit): 19 people, 67.86%
Emotional Distress: 17 people, 60.71%
Urinary Tract Infection: 17 people, 60.71%
Acute Kidney Failure: 17 people, 60.71%
Dyspnea (difficult or laboured breathing): 17 people, 60.71%
Stress And Anxiety: 17 people, 60.71%
Pain In Extremity: 17 people, 60.71%
Spinal Osteoarthritis (joint cartilage loss in spine): 17 people, 60.71%
Intervertebral Disc Protrusion (spinal disc protrusion): 16 people, 57.14%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 16 people, 57.14%

What are the existing conditions these people have? *

Breast Cancer: 11 people, 39.29%
Stress And Anxiety: 9 people, 32.14%
Metastases To Bone (cancer spreads to bone): 7 people, 25.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 21.43%
Osteoporosis (bones weak and more likely to break): 4 people, 14.29%
Multiple Myeloma (cancer of the plasma cells): 4 people, 14.29%
Neuralgia (pain in one or more nerves): 3 people, 10.71%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 10.71%
Bone Pain: 3 people, 10.71%
Breast Cancer Metastatic: 3 people, 10.71%

* Approximation only. Some reports may have incomplete information.

Do you take Naprosyn and have Hypertonic bladder?

- Check whether Hypertonic bladder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naprosyn:

Naprosyn (16,738 reports)

Browse all side effects of Naprosyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertonic bladder:

Hypertonic bladder (617 drugs)

Browse all the conditions that are associated with Hypertonic bladder:

Hypertonic bladder (508 conditions)

Drugs similar to Naprosyn and Hypertonic bladder :

How the study uses the data?

The study uses data from the FDA. It is based on naproxen (the active ingredients of Naprosyn) and Naprosyn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.