Naproxen sodium and Anhedonia - a phase IV clinical study of FDA data

Summary:

Anhedonia is reported as a side effect among people who take Naproxen sodium (naproxen sodium), especially for people who are female, 40-49 old, also take Yaz, and have Premenstrual syndrome.

The phase IV clinical study analyzes which people have Anhedonia when taking Naproxen sodium. It is created by eHealthMe based on reports of 10,713 people who have side effects when taking Naproxen sodium from the FDA, and is updated regularly.

What is Naproxen sodium?

Naproxen sodium has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 11,252 Naproxen sodium users. Check the latest studies of Naproxen sodium.

What is Anhedonia?

Anhedonia (inability to experience pleasure from activities usually found enjoyable) is found to be associated with 1,509 drugs and 1,275 conditions by eHealthMe. Check the latest studies of Anhedonia.



On Jul, 14, 2026

10,713 people reported to have side effects when taking Naproxen sodium.
Among them, 17 people (0.16%) have Anhedonia.

Could Naproxen sodium cause Anhedonia?

Among these 17 people:

What is the gender of people who have Anhedonia when taking Naproxen sodium? *

  • female: 82.35 %
  • male: 17.65 %

What is the age of people who have Anhedonia when taking Naproxen sodium? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6.25 %
  • 20-29: 6.25 %
  • 30-39: 31.25 %
  • 40-49: 37.5 %
  • 50-59: 18.75 %
  • 60+: 0.0 %

What are other drugs people take besides Naproxen sodium? *

  1. Yaz: 5 people, 29.41%
  2. Acetaminophen: 4 people, 23.53%
  3. Trasylol: 4 people, 23.53%
  4. Lasix: 4 people, 23.53%
  5. Ibuprofen: 4 people, 23.53%
  6. Yasmin: 4 people, 23.53%
  7. Heparin: 3 people, 17.65%
  8. Versed: 3 people, 17.65%
  9. Furosemide: 3 people, 17.65%
  10. Amoxicillin: 3 people, 17.65%

What are other side effects people have besides Anhedonia? *

  1. Stress And Anxiety: 16 people, 94.12%
  2. Emotional Distress: 9 people, 52.94%
  3. Injury: 9 people, 52.94%
  4. Fear: 7 people, 41.18%
  5. Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 23.53%
  6. Acute Kidney Failure: 4 people, 23.53%
  7. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 23.53%
  8. Renal Injury (kidney injury): 3 people, 17.65%
  9. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 3 people, 17.65%
  10. Joint Pain: 3 people, 17.65%

What are the existing conditions these people have? *

  1. Premenstrual Syndrome: 3 people, 17.65%
  2. Prostatitis (inflammation of the prostate gland): 2 people, 11.76%
  3. Hiv Infection: 2 people, 11.76%
  4. Birth Control: 2 people, 11.76%
  5. Acne (skin problems that cause pimples): 2 people, 11.76%
  6. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 5.88%
  7. Pneumonia: 1 person, 5.88%
  8. Nuclear Magnetic Resonance Imaging Brain: 1 person, 5.88%
  9. Neuralgia (pain in one or more nerves): 1 person, 5.88%
  10. Menstrual Disorder (disease of menstrual cycle): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Naproxen sodium and have Anhedonia?

- Check whether Anhedonia is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Naproxen sodium:

Anhedonia treatments and more:

How severe was Anhedonia and when was it recovered:

Expand to all the drugs that have ingredients of naproxen sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naproxen sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anhedonia:

Browse all the conditions that are associated with Anhedonia:


How the study uses the data?

The study uses data from the FDA. It is based on naproxen sodium (the active ingredients of Naproxen sodium) and Naproxen sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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