Narcan and Dry mouth - a phase IV clinical study of FDA data

Summary:

Dry mouth is reported as a side effect among people who take Narcan (naloxone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lyrica, and have Osteoporosis.

The phase IV clinical study analyzes which people have Dry mouth when taking Narcan. It is created by eHealthMe based on reports of 3,672 people who have side effects when taking Narcan from the FDA, and is updated regularly.

What is Narcan?

Narcan has active ingredients of naloxone hydrochloride. eHealthMe is studying from 3,687 Narcan users. Check the latest studies of Narcan.

What is Dry mouth?

Dry mouth is found to be associated with 2,094 drugs and 2,492 conditions by eHealthMe. Check the latest studies of Dry mouth.

On Jul, 21, 2026

3,672 people reported to have side effects when taking Narcan.
Among them, 28 people (0.76%) have Dry mouth.

Among these 28 people:

How long have people been on Narcan when they have Dry mouth? *

What is the gender of people who have Dry mouth when taking Narcan? *

female: 81.48 %
male: 18.52 %

What is the age of people who have Dry mouth when taking Narcan? *

What are other drugs people take besides Narcan? *

What are other side effects people have besides Dry mouth? *

Nausea (feeling of having an urge to vomit): 13 people, 46.43%
Weakness: 13 people, 46.43%
Pain: 13 people, 46.43%
Chest Pain: 11 people, 39.29%
Back Pain: 10 people, 35.71%
Memory Loss: 9 people, 32.14%
Dyspnea (difficult or laboured breathing): 9 people, 32.14%
Dizziness: 9 people, 32.14%
Depression: 9 people, 32.14%
Muscle Aches (muscle pain): 8 people, 28.57%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 6 people, 21.43%
Overdose: 4 people, 14.29%
Pain: 3 people, 10.71%
Diabetes: 3 people, 10.71%
Skin Ulcer: 3 people, 10.71%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 7.14%
Insomnia (sleeplessness): 2 people, 7.14%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 7.14%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 7.14%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Narcan and have Dry mouth?

- Check whether Dry mouth is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Narcan:

Narcan (3,687 reports)

Dry mouth treatments and more:

Dry mouth (97,956 reports)

Browse all side effects of Narcan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dry mouth:

Dry mouth (2,094 drugs)

Browse all the conditions that are associated with Dry mouth:

Dry mouth (2,492 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on naloxone hydrochloride (the active ingredients of Narcan) and Narcan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.