Narcan and Premature delivery - a phase IV clinical study of FDA data

Summary:

Premature delivery is reported as a side effect among people who take Narcan (naloxone hydrochloride), especially for people who are also take Vyvanse, and have Quit smoking.

The phase IV clinical study analyzes which people have Premature delivery when taking Narcan. It is created by eHealthMe based on reports of 3,672 people who have side effects when taking Narcan from the FDA, and is updated regularly.

What is Narcan?

Narcan has active ingredients of naloxone hydrochloride. eHealthMe is studying from 3,687 Narcan users. Check the latest studies of Narcan.

What is Premature delivery?

Premature delivery is found to be associated with 557 drugs and 731 conditions by eHealthMe. Check the latest studies of Premature delivery.



On Jul, 12, 2026

3,672 people reported to have side effects when taking Narcan.
Among them, 41 people (1.12%) have Premature delivery.

Could Narcan cause Premature delivery?

Among these 41 people:

What are other drugs people take besides Narcan? *

  1. Vyvanse: 32 people, 78.05%
  2. Abilify: 23 people, 56.10%
  3. Lisdexamfetamine Dimesylate: 9 people, 21.95%
  4. Nicotine: 8 people, 19.51%
  5. Naloxone: 8 people, 19.51%
  6. Diazepam: 8 people, 19.51%
  7. Buprenorphine: 7 people, 17.07%
  8. Aripiprazole: 7 people, 17.07%
  9. Buprenorphine Hydrochloride: 5 people, 12.20%
  10. Naloxone Hydrochloride: 4 people, 9.76%

What are other side effects people have besides Premature delivery? *

  1. Maternal Exposure During Pregnancy (use of substance during pregnancy): 41 people, 100.00%
  2. Premature Baby: 21 people, 51.22%
  3. Rhesus Incompatibility (a condition that occurs during pregnancy if a woman has rh-negative blood and her baby has rh-positive blood): 7 people, 17.07%
  4. Breech Presentation: 6 people, 14.63%
  5. Jaundice Neonatal (yellowing of skin in neonate): 4 people, 9.76%
  6. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 4 people, 9.76%
  7. Foetal Distress Syndrome (altered heart rate or rhythm and leading tocompromised blood flow or changes in blood chemistry of foetus): 4 people, 9.76%
  8. Drug Withdrawal Syndrome Neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother): 4 people, 9.76%

What are the existing conditions these people have? *

  1. Quit Smoking: 17 people, 41.46%
  2. Drug Dependence: 7 people, 17.07%
  3. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 4 people, 9.76%
  4. Postpartum Disorder (moderate to severe depression in a woman after she has given birth): 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Narcan and have Premature delivery?

- Check whether Premature delivery is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Narcan:

Premature delivery treatments and more:

How severe was Premature delivery and when was it recovered:

Expand to all the drugs that have ingredients of naloxone hydrochloride:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Narcan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Premature delivery:

Browse all the conditions that are associated with Premature delivery:


How the study uses the data?

The study uses data from the FDA. It is based on naloxone hydrochloride (the active ingredients of Narcan) and Narcan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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