Natrecor and International normalised ratio increased - a phase IV clinical study of FDA data

Summary:

International normalised ratio increased is reported as a side effect among people who take Natrecor (nesiritide recombinant), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Coumadin, and have Bleeding disorders.

The phase IV clinical study analyzes which people have International normalised ratio increased when taking Natrecor. It is created by eHealthMe based on reports of 501 people who have side effects when taking Natrecor from the FDA, and is updated regularly.

What is Natrecor?

Natrecor has active ingredients of nesiritide recombinant. eHealthMe is studying from 503 Natrecor users. Check the latest studies of Natrecor.

What is International normalised ratio increased?

International normalised ratio increased is found to be associated with 1,335 drugs and 1,727 conditions by eHealthMe. Check the latest studies of International normalised ratio increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 29, 2026

501 people reported to have side effects when taking Natrecor.
Among them, 12 people (2.4%) have International normalised ratio increased.

Could Natrecor cause International normalised ratio increased?

Among these 12 people:

How long have people been on Natrecor when they have International normalised ratio increased? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have International normalised ratio increased when taking Natrecor? *

  • female: 50 %
  • male: 50 %

What is the age of people who have International normalised ratio increased when taking Natrecor? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 28.57 %
  • 60+: 71.43 %

What are other drugs people take besides Natrecor? *

  1. Coumadin: 8 people, 66.67%
  2. Coreg: 7 people, 58.33%
  3. Digoxin: 7 people, 58.33%
  4. Lasix: 7 people, 58.33%
  5. Lovenox: 6 people, 50.00%
  6. Albuterol: 6 people, 50.00%
  7. Spironolactone: 4 people, 33.33%
  8. Aspirin: 4 people, 33.33%
  9. Levaquin: 4 people, 33.33%
  10. Klor-Con: 4 people, 33.33%

What are other side effects people have besides International normalised ratio increased? *

  1. Cardiac Failure Congestive: 6 people, 50.00%
  2. Constipation: 5 people, 41.67%
  3. Mitral Valve Incompetence (inefficient heart valve): 5 people, 41.67%
  4. Oedema Peripheral (superficial swelling): 5 people, 41.67%
  5. Hyperkalemia (damage to or disease of the kidney): 5 people, 41.67%
  6. Pneumonia: 4 people, 33.33%
  7. Blood Creatinine Increased: 4 people, 33.33%
  8. Chronic Renal Failure (kidney failure): 4 people, 33.33%
  9. Injury: 4 people, 33.33%
  10. Dyspnea (difficult or laboured breathing): 4 people, 33.33%

What are the existing conditions these people have? *

  1. Bleeding Disorders: 2 people, 16.67%
  2. Impaired Gastric Emptying: 1 person, 8.33%
  3. Hypertrophic Cardiomyopathy (a condition in which the heart muscle becomes abnormally thick): 1 person, 8.33%
  4. Constipation: 1 person, 8.33%
  5. Cardiac Disorder: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Natrecor and have International normalised ratio increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Natrecor:

International normalised ratio increased treatments and more:

How severe was International normalised ratio increased and when was it recovered:

Expand to all the drugs that have ingredients of nesiritide recombinant:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Natrecor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with International normalised ratio increased:

Browse all the conditions that are associated with International normalised ratio increased:


How the study uses the data?

The study uses data from the FDA. It is based on nesiritide recombinant (the active ingredients of Natrecor) and Natrecor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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