Nembutal and Hypotension - a phase IV clinical study of FDA data

Summary:

Hypotension is reported as a side effect among people who take Nembutal (pentobarbital), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Propofol, and have Sedation.

The phase IV clinical study analyzes which people have Hypotension when taking Nembutal. It is created by eHealthMe based on reports of 138 people who have side effects when taking Nembutal from the FDA, and is updated regularly.

What is Nembutal?

Nembutal has active ingredients of pentobarbital. eHealthMe is studying from 150 Nembutal users. Check the latest studies of Nembutal.

What is Hypotension?

Hypotension (abnormally low blood pressure) is found to be associated with 3,364 drugs and 4,753 conditions by eHealthMe. Check the latest studies of Hypotension.



On Jul, 04, 2026

138 people reported to have side effects when taking Nembutal.
Among them, 12 people (8.7%) have Hypotension.

Could Nembutal cause Hypotension?

Among these 12 people:

How long have people been on Nembutal when they have Hypotension? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypotension when taking Nembutal? *

  • female: 36.36 %
  • male: 63.64 %

What is the age of people who have Hypotension when taking Nembutal? *

  • 0-1: 9.09 %
  • 2-9: 18.18 %
  • 10-19: 18.18 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 9.09 %
  • 50-59: 9.09 %
  • 60+: 36.36 %

What are other drugs people take besides Nembutal? *

  1. Lorazepam: 5 people, 41.67%
  2. Propofol: 5 people, 41.67%
  3. Zolpidem Tartrate: 4 people, 33.33%
  4. Omeprazole: 4 people, 33.33%
  5. Naloxone Hydrochloride: 4 people, 33.33%
  6. Mupirocin: 4 people, 33.33%
  7. Moxifloxacin: 4 people, 33.33%
  8. Morphine Sulfate: 4 people, 33.33%
  9. Magnesium Sulfate: 4 people, 33.33%
  10. Lanthanum Carbonate: 4 people, 33.33%

What are other side effects people have besides Hypotension? *

  1. Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 4 people, 33.33%
  2. Cerebral Haemorrhage (bleeding within the brain): 4 people, 33.33%
  3. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 3 people, 25.00%
  4. Anaemia (lack of blood): 3 people, 25.00%
  5. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 3 people, 25.00%
  6. Cardiac Arrest: 3 people, 25.00%
  7. Septic Shock (shock due to blood infection): 3 people, 25.00%
  8. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 3 people, 25.00%
  9. Encephalopathy (functioning of the brain is affected by some agent or condition): 3 people, 25.00%
  10. Fall: 3 people, 25.00%

What are the existing conditions these people have? *

  1. Sedation: 4 people, 33.33%
  2. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Nembutal and have Hypotension?

- Check whether Hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nembutal:

Hypotension treatments and more:

How severe was Hypotension and when was it recovered:

Expand to all the drugs that have ingredients of pentobarbital:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nembutal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypotension:

Browse all the conditions that are associated with Hypotension:


How the study uses the data?

The study uses data from the FDA. It is based on pentobarbital (the active ingredients of Nembutal) and Nembutal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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