Nesina and Hypothyroidism - a phase IV clinical study of FDA data

Summary:

Hypothyroidism is reported as a side effect among people who take Nesina (alogliptin benzoate), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Opdivo, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Hypothyroidism when taking Nesina. It is created by eHealthMe based on reports of 2,291 people who have side effects when taking Nesina from the FDA, and is updated regularly.

What is Nesina?

Nesina has active ingredients of alogliptin benzoate. eHealthMe is studying from 2,297 Nesina users. Check the latest studies of Nesina.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,616 drugs and 2,600 conditions by eHealthMe. Check the latest studies of Hypothyroidism.

On Jul, 17, 2026

2,291 people reported to have side effects when taking Nesina.
Among them, 11 people (0.48%) have Hypothyroidism.

Among these 11 people:

How long have people been on Nesina when they have Hypothyroidism? *

What is the gender of people who have Hypothyroidism when taking Nesina? *

female: 72.73 %
male: 27.27 %

What is the age of people who have Hypothyroidism when taking Nesina? *

What are other drugs people take besides Nesina? *

What are other side effects people have besides Hypothyroidism? *

Pneumonia: 5 people, 45.45%
Cardiac Failure: 3 people, 27.27%
Liver Disorder (liver diseases): 3 people, 27.27%
Thyroiditis (inflammation of thyroid gland): 3 people, 27.27%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 27.27%
Diarrhea: 3 people, 27.27%
Weakness: 2 people, 18.18%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 2 people, 18.18%
Insomnia (sleeplessness): 2 people, 18.18%
Nausea (feeling of having an urge to vomit): 2 people, 18.18%

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 5 people, 45.45%
Diabetes: 4 people, 36.36%
Type 2 Diabetes: 3 people, 27.27%
Nausea And Vomiting: 2 people, 18.18%
Glycosylated Haemoglobin Increased: 1 person, 9.09%
Cancer Pain: 1 person, 9.09%
Cardiac Failure Chronic: 1 person, 9.09%
Constipation: 1 person, 9.09%
Enlarged Prostate: 1 person, 9.09%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Nesina and have Hypothyroidism?

- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nesina:

Nesina (2,297 reports)

Hypothyroidism treatments and more:

Hypothyroidism (168,065 reports)

Browse all side effects of Nesina:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothyroidism:

Hypothyroidism (1,616 drugs)

Browse all the conditions that are associated with Hypothyroidism:

Hypothyroidism (2,600 conditions)

Related publications that referenced our studies

Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .

How the study uses the data?

The study uses data from the FDA. It is based on alogliptin benzoate (the active ingredients of Nesina) and Nesina (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.