Neupro and Feeling cold - a phase IV clinical study of FDA data

Summary:

Feeling cold is reported as a side effect among people who take Neupro (rotigotine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Sinemet, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Feeling cold when taking Neupro. It is created by eHealthMe based on reports of 11,313 people who have side effects when taking Neupro from the FDA, and is updated regularly.

What is Neupro?

Neupro has active ingredients of rotigotine. It is often used in parkinson's disease. eHealthMe is studying from 11,393 Neupro users. Check the latest studies of Neupro.

What is Feeling cold?

Feeling cold is found to be associated with 1,337 drugs and 1,620 conditions by eHealthMe. Check the latest studies of Feeling cold.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

11,313 people reported to have side effects when taking Neupro.
Among them, 22 people (0.19%) have Feeling cold.

Among these 22 people:

How long have people been on Neupro when they have Feeling cold? *

What is the gender of people who have Feeling cold when taking Neupro? *

female: 31.82 %
male: 68.18 %

What is the age of people who have Feeling cold when taking Neupro? *

What are other drugs people take besides Neupro? *

What are other side effects people have besides Feeling cold? *

Stress And Anxiety: 12 people, 54.55%
Feeling Abnormal: 11 people, 50.00%
Insomnia (sleeplessness): 10 people, 45.45%
Balance Disorder: 10 people, 45.45%
Fever: 10 people, 45.45%
Nausea (feeling of having an urge to vomit): 10 people, 45.45%
Infection: 9 people, 40.91%
Fall: 9 people, 40.91%
Dyskinesia (abnormality or impairment of voluntary movement): 9 people, 40.91%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 9 people, 40.91%

What are the existing conditions these people have? *

Sleep Disorder: 3 people, 13.64%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 13.64%
Psychotic Disorder: 2 people, 9.09%
Hallucinations (sensations that appear real but are created by your mind): 2 people, 9.09%
Fatigue (feeling of tiredness): 2 people, 9.09%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 4.55%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 1 person, 4.55%
Iron Deficiency: 1 person, 4.55%
Hypersensitivity: 1 person, 4.55%
Fibroma (tumours that are composed of fibrous or connective tissue): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Neupro and have Feeling cold?

- Check whether Feeling cold is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Neupro:

Neupro (11,393 reports)

Feeling cold treatments and more:

Feeling cold (33,886 reports)

Browse all side effects of Neupro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Feeling cold:

Feeling cold (1,337 drugs)

Browse all the conditions that are associated with Feeling cold:

Feeling cold (1,620 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rotigotine (the active ingredients of Neupro) and Neupro (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.